CAJ | 학술논문

目的：观察腰痹颗粒治疗退行性腰椎管狭窄症的疗效。方法：采用多中心、中央随机对照的方法，将175例随机纳入治疗组（口服腰痹颗粒）92例和对照组（口服氨糖美辛片）83例。疗程2周。采用日本整形外科学会（ Japanese Orthopedic Associa-tion，JOA）对总体疗效和计步器对间歇性跛行进行疗效评价。结果：治疗组有效率为86.8％，优良率为54.5％；对照组有效率为58.8％，优良率为23.8％，治疗组明显优于对照组（ P＝0.001）。除了步距之外，腰痹颗粒对步行距离、步行时间和步行速度的改善也优于对照组（P＜0.05）。45 d的近期随访结果与疗程结束时相似。结论：腰痹汤治疗退行性腰椎管狭窄症具有较好的临床疗效，并能明显改善间歇性跛行状态。
목적：관찰요비과립치료퇴행성요추관협착증적료효。방법：채용다중심、중앙수궤대조적방법，장175례수궤납입치료조（구복요비과립）92례화대조조（구복안당미신편）83례。료정2주。채용일본정형외과학회（ Japanese Orthopedic Associa-tion，JOA）대총체료효화계보기대간헐성파행진행료효평개。결과：치료조유효솔위86.8％，우량솔위54.5％；대조조유효솔위58.8％，우량솔위23.8％，치료조명현우우대조조（ P＝0.001）。제료보거지외，요비과립대보행거리、보행시간화보행속도적개선야우우대조조（P＜0.05）。45 d적근기수방결과여료정결속시상사。결론：요비탕치료퇴행성요추관협착증구유교호적림상료효，병능명현개선간헐성파행상태。
Objective:To investigate the outcome of degenerative lumbar canal stenosis treated with Yaobi granules .Methods: Totally 175 cases were separated randomly into Treatment Group (92 cases treated with Yaobi granules ) and Control Group B (83 cases treated with Glucosamine Indomethacin entric-coated tablets ) .The outcome of 2-week treatment and 6-week follow up were appraised by the JOA criteria and the neurogenic claudication by pedometer .Results: Treatment Group demonstrated better effect than the Control Group.Treatment Group had an effective rate of 86.8%and excellent rate of 54.5%and showed a significant difference (P=0.001) compared with the Control Group (effective rate 58.8%and excellent rate 23.8%).Apart from footsteps, walking distance, time and speed also improved significantly in treatment Group than that in the Control Group (P<0.05).During the 6-week follow-up, results were similar as above .Conclusion:Yaobi granules showed positive effect in treating degenerative lumbar canal stenosis and in enhan -cing walking ability of patients .