CAJ | 학술논문

目的探讨阿魏酸钠(川芎素)、小牛血清去蛋白对急性一氧化碳中毒的治疗作用.方法将有昏迷史的75例急性一氧化碳中毒患者按随机数字表法分为治疗组(37例)和对照组(38例),两组均应用高压氧、高流量吸氧及对症支持治疗,治疗组加用川芎素、小牛血清去蛋白；对照组加用胞磷胆碱等药物.结果治疗组心肌损伤发生率和严重程度评分均低于对照组(P＜0.05),昏迷时间和住院时间均短于对照组(P＜0.05).治疗组迟发性脑病发生率为2.7％(1/37),对照组为23.7％ (9/38),两组比较差异有统计学意义(P＜0.05)；治疗组病死率为2.7％(1/37),对照组为5.3％(2/38),两组比较差异无统计学意义(P＞0.05).结论川芎素、小牛血清去蛋白对急性一氧化碳中毒有较好的治疗作用.
목적 탐토아위산납(천궁소)、소우혈청거단백대급성일양화탄중독적치료작용.방법 장유혼미사적75례급성일양화탄중독환자안수궤수자표법분위치료조(37례)화대조조(38례),량조균응용고압양、고류량흡양급대증지지치료,치료조가용천궁소、소우혈청거단백；대조조가용포린담감등약물.결과 치료조심기손상발생솔화엄중정도평분균저우대조조(P＜0.05),혼미시간화주원시간균단우대조조(P＜0.05).치료조지발성뇌병발생솔위2.7％(1/37),대조조위23.7％ (9/38),량조비교차이유통계학의의(P＜0.05)；치료조병사솔위2.7％(1/37),대조조위5.3％(2/38),량조비교차이무통계학의의(P＞0.05).결론 천궁소、소우혈청거단백대급성일양화탄중독유교호적치료작용.
Objective Discuss the treatment effect of sodium ferulate,deproteinized calf serum and high pressure oxygen on acute carbon monoxide poisoning.Methods Seventy-five cases with coma acute carbon monoxide poisoning were randomly divided into two groups:the treated group (37 cases) and the control group (38 cases).The two groups were treated with high pressure oxygen,high flow oxygen uptake and support treatment,The treated group were treated with sodium ferulate and deproteinized calf serum.The control group were treated with citicoline act medicaments.Result The occurrence and injury degree of myocardial damage and delayed encephalopathy were markedly attenuated (P ＜ 0.05),the time of coma was obviously decreased (P ＜0.01),the death rate was obviously difference (P ＜0.05) in the treated group compared with the control group.Conclusion Sodium ferulate,deproteinized calf serum injection possess obviously effect on acute carbon monoxide poisoning.