CAJ | 학술논문

建立了高效液相色谱法测定头孢西酮钠的有关物质。采用十八烷基键合硅胶，流动相为0.02 mol/L 磷酸二氢铵缓冲液(0.1 mol/L 氢氧化钠溶液调至 pH 5.0)-乙腈，梯度洗脱，流速为1 ml/min，检测波长278 nm。结果显示，头孢西酮钠与各杂质分离良好。
건립료고효액상색보법측정두포서동납적유관물질。채용십팔완기건합규효，류동상위0.02 mol/L 린산이경안완충액(0.1 mol/L 경양화납용액조지 pH 5.0)-을정，제도세탈，류속위1 ml/min，검측파장278 nm。결과현시，두포서동납여각잡질분리량호。
An HPLC method was established for the determination of the related substances of cefazedone sodium. A C18 column was used, with the mobile phase of 0.02 mol/L ammonium dihydrogen phosphate buffer (adjusted to pH 5.0 by 0.1mol/L NaOH solution)-acetonitrile by gradient elution. The flow rate was 1ml/min. The detection wavelength was 278 nm. The result showed that cefazedone sodium and its related substances were isolated well.