中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2013年
20期
154-155
,共2页
娄涛%欧阳华%王章元%娄秀丽%耿彩虹%李强%穆俊林%张朝辉
婁濤%歐暘華%王章元%婁秀麗%耿綵虹%李彊%穆俊林%張朝輝
루도%구양화%왕장원%루수려%경채홍%리강%목준림%장조휘
躯体化障碍%述情障碍%事件相关电位%P300
軀體化障礙%述情障礙%事件相關電位%P300
구체화장애%술정장애%사건상관전위%P300
Somatization disorder%Alexithymia%event related potential%P300
目的:探讨躯体化障碍患者的述情障碍与认知功能的关系。方法56例躯体化障碍患者和50名正常对照者进行多伦多述情障碍量表(Toronto alexithymia scale,TAS-20)和事件相关电位P300测定,分析所得结果。结果躯体化障碍组的TAS总分、F1、F2、F3因子分均高于正常对照组,差异有统计学意义(P<0.05);躯体化障碍组的TAS总分与N2、P2、P3潜伏期成正相关,与P2、P3波幅成负相关(P<0.05或P<0.01);F1与P2波幅呈负相关,与N2、P3潜伏期正相关;F2与P2、P3波幅呈负相关,与N2、P2及P3潜伏期正相关(P<0.05或P<0.01);F3与P3潜伏期成正相关,与P2、P3波幅呈负相关(P<0.05或P<0.01)。结论躯体化障碍患者存在述情障碍,且述情障碍可能影响了患者的认知功能。
目的:探討軀體化障礙患者的述情障礙與認知功能的關繫。方法56例軀體化障礙患者和50名正常對照者進行多倫多述情障礙量錶(Toronto alexithymia scale,TAS-20)和事件相關電位P300測定,分析所得結果。結果軀體化障礙組的TAS總分、F1、F2、F3因子分均高于正常對照組,差異有統計學意義(P<0.05);軀體化障礙組的TAS總分與N2、P2、P3潛伏期成正相關,與P2、P3波幅成負相關(P<0.05或P<0.01);F1與P2波幅呈負相關,與N2、P3潛伏期正相關;F2與P2、P3波幅呈負相關,與N2、P2及P3潛伏期正相關(P<0.05或P<0.01);F3與P3潛伏期成正相關,與P2、P3波幅呈負相關(P<0.05或P<0.01)。結論軀體化障礙患者存在述情障礙,且述情障礙可能影響瞭患者的認知功能。
목적:탐토구체화장애환자적술정장애여인지공능적관계。방법56례구체화장애환자화50명정상대조자진행다륜다술정장애량표(Toronto alexithymia scale,TAS-20)화사건상관전위P300측정,분석소득결과。결과구체화장애조적TAS총분、F1、F2、F3인자분균고우정상대조조,차이유통계학의의(P<0.05);구체화장애조적TAS총분여N2、P2、P3잠복기성정상관,여P2、P3파폭성부상관(P<0.05혹P<0.01);F1여P2파폭정부상관,여N2、P3잠복기정상관;F2여P2、P3파폭정부상관,여N2、P2급P3잠복기정상관(P<0.05혹P<0.01);F3여P3잠복기성정상관,여P2、P3파폭정부상관(P<0.05혹P<0.01)。결론구체화장애환자존재술정장애,차술정장애가능영향료환자적인지공능。
Objective To explore the relationship between alexithymia and cognitive function in patients with somatization disorder(SD). Methods 56 SD patients and 50 controllers were evaluated with Toronto alexithymia scale(TAS-20) and event related potential P300,the results were analyzed with t-test and correlation analysis. Results The total score and scores of F1,F2 and F3 of TAS-20 in somatization disorder patients were higher than those in controllers(P<0.05).The total score of TAS-20 correlated positively with the latency of N2,P2 and P3,and negatively with amplitude of P2 and P3.The score of F1 was correlation with N2,P2 and P3 positively, and amplitude of P2 and P3 negatively. thescore of F2 was positive correlation with latency of N2,P2 and P3 and negative correlation with amplitude of P2 and P3.The score of F3 was positive correlation with latency of P3 and negative correlation with amplitude of P2 and P3. Conclusion Somatization disorder patients have obvous alexithymia,and alexithymia is correlation with cognition,which provide cue for intervention of cognitive impairment.