CAJ | 학술논문

目的：探讨脑钠肽联合胱抑素C检测在慢性心力衰竭患者中的应用效果及价值。方法随机抽取我院在2012年5月～2013年5月期间收治的慢性心力衰竭患者63例的临床资料进行回顾性分析，将本组患者按照检测方法的不同分为三组，A组、B组和C组，每组A组例行单纯的胱抑素C检测，B组例行单纯的脑钠肽检测，C组例行脑钠肽、胱抑素C联合检测，针对三组患者的检测结果以及在慢性心力衰竭患者诊断中的应用效果进行系统评价。结果A组诊断正确率为71.4%，B组诊断正确率为66.7%，C组诊断正确率为95.2%，A组和B组的诊断结果差异不显著，不具有统计学意义（P＞0.05）；C组诊断正确率明显高于A组和B组，差异显著，具有统计学意义（P＜0.05）。结论采用脑钠肽，胱抑素C联合检测应用慢性心力衰竭患者的诊断，可以有效地提高诊断准确率，为慢性心力衰竭患者正确诊断与治疗提供科学依据，值得临床推广与应用。
목적：탐토뇌납태연합광억소C검측재만성심력쇠갈환자중적응용효과급개치。방법수궤추취아원재2012년5월～2013년5월기간수치적만성심력쇠갈환자63례적림상자료진행회고성분석，장본조환자안조검측방법적불동분위삼조，A조、B조화C조，매조A조례행단순적광억소C검측，B조례행단순적뇌납태검측，C조례행뇌납태、광억소C연합검측，침대삼조환자적검측결과이급재만성심력쇠갈환자진단중적응용효과진행계통평개。결과A조진단정학솔위71.4%，B조진단정학솔위66.7%，C조진단정학솔위95.2%，A조화B조적진단결과차이불현저，불구유통계학의의（P＞0.05）；C조진단정학솔명현고우A조화B조，차이현저，구유통계학의의（P＜0.05）。결론채용뇌납태，광억소C연합검측응용만성심력쇠갈환자적진단，가이유효지제고진단준학솔，위만성심력쇠갈환자정학진단여치료제공과학의거，치득림상추엄여응용。
Objective To investigate the application effect and value of combined detection of brain natriuretic peptide and cystatin C in the patients with chronic heart failure. Methods The clinical data of 63 cases with chronic heart failure chosen randomly in our hospital during May 2012 to May 2013 were retrospectively analyzed. The patients were divided into three groups according to different detection methods, namely group A, group B and group C. The patients in group A were detected cystatin C, that in group B were detected brain natriuretic peptide, while that in group C were detected brain natriuretic peptide and cystatin C. The detection results of patients in three groups and their application effects in the diagnosis of patients with chronic heart failure were systematically evaluated. Results The rate of correct diagnosis in group A was 71.4%, that in group B was 66.7%, and that in group C was 95.2%. The difference was not statistically significant in the rate of correct diagnosis between group A and group B(P > 0.05);The rate of correct diagnosis in group C was significantly higher than that in group A and group B, the difference was statistically significant(P < 0.05). Conclusion Combined detection of brain natriuretic peptide and cystatin C in the diagnosis of patients with chronic heart failure can effectively improve the rate of correct diagnosis, and provide scientific basis for correct diagnosis and treatment in patients with chronic heart failure, and it is worthy of clinical promotion and application.