CAJ | 학술논문

目的：探讨恩度联合顺铂治疗晚期非小细胞肺癌的临床效果。方法选择2010年2月～2013年2月在本院肿瘤内科治疗的中晚期非小细胞肺癌患者117例患者，随机分为单纯化疗组（对照组）58例和恩度联合顺铂组（观察组）59例，观察两组患者的临床疗效及不良反应。结果观察组总有效率为59.32%，对照组总有效率为37.93%；两组比较，差异有统计学意义（P＜0.05）。两组不良反应比较，差异无统计学意义（P＞0.05）。结论恩度联合顺铂胸腔内注射治疗晚期非小细胞肺癌临床疗效显著，值得在临床推广应用。
목적：탐토은도연합순박치료만기비소세포폐암적림상효과。방법선택2010년2월～2013년2월재본원종류내과치료적중만기비소세포폐암환자117례환자，수궤분위단순화료조（대조조）58례화은도연합순박조（관찰조）59례，관찰량조환자적림상료효급불량반응。결과관찰조총유효솔위59.32%，대조조총유효솔위37.93%；량조비교，차이유통계학의의（P＜0.05）。량조불량반응비교，차이무통계학의의（P＞0.05）。결론은도연합순박흉강내주사치료만기비소세포폐암림상료효현저，치득재림상추엄응용。
Objective To investigate the clinical Effect of Endostar combined with cisplatin intrapleural injection in the treatment of advanced non-small cell lung cancer. Methods 117 cases of patients withadvanced non small cell lung cancer patients In 2010 February-2013 year in February were collected in the hospital,who were randomly divided into chemotherapy group(control group) 58 cases and Endostar combined with cisplatin group(observation group)59 cases,The clinicalefficacy and adverse reactions of two groups of patients observation were observed. Results The observation group the total effective rate was 59.32%,total effective rate of the control group was 37.93%; the two groups,the difference was statistically significant(P<0.05). Adverse reactions of two groups, the difference was not statistically significant(P > 0.05). Conclusion Endostar combined with cisplatin intrapleural injection in the treatment of advanced non-small cell lung cancer clinical efficacy significantly,it is worth in clinical application..