CAJ | 학술논문

目的：探讨辛伐他汀对早期糖尿病肾病尿微球蛋白的影响。方法选取我院2012年1月～10月间住院糖尿病肾病患者123例，根据治疗方法不同分为治疗组62例，对照组61例，治疗组在降糖降压基础上予以辛伐他汀治疗，对照组予以降糖降压治疗，治疗30d后，观察尿微球蛋白改变。结果治疗组治疗前后和对照组比较，尿微球蛋白显著下降。结论辛伐他汀对早期糖尿病肾病尿微球蛋白有降低作用。
목적：탐토신벌타정대조기당뇨병신병뇨미구단백적영향。방법선취아원2012년1월～10월간주원당뇨병신병환자123례，근거치료방법불동분위치료조62례，대조조61례，치료조재강당강압기출상여이신벌타정치료，대조조여이강당강압치료，치료30d후，관찰뇨미구단백개변。결과치료조치료전후화대조조비교，뇨미구단백현저하강。결론신벌타정대조기당뇨병신병뇨미구단백유강저작용。
Objective To investigate the influence of simvastatin on the urine microglobulin of patients with early diabetic nephropathy. Methods 123 patients with diabetic nephropathy who were hospitalized in our hospital from January 2012 to October 2012 were selected and divided into the treatment group with 62 patients and the control group with 61 patients according to the treatment method. The treatment group was given simvastatin treatment on the basis of hypoglycemic and antihypertensive treatment. The control group was given hypoglycemic and antihypertensive treatment. The changes of urine microglobulin 30 days after the treatment were observed. Results After the treatment, the microglobulin of the treatment group reduced significantly compared to that of the control group. Conclusion Simvastatin has an effect on reducing the microglobulin of patients with early diabetic nephropathy.