CAJ | 학술논문

目的：探讨中西医结合治疗矽肺患者的有效性和安全性。方法选取我院收治的65例矽肺患者，根据治疗方法不同分为对照组33例（口服氨茶碱，抗感染和必要时吸氧等常规治疗）和治疗组32例（在常规治疗的基础上给予中药“自拟克矽汤”水煎服治疗）。比较两组患者的肺功能变化情况、治疗总有效率和不良反应发生率的差异。结果治疗后所有患者的肺活量（VC）、第1秒用力呼气容积（FEV1）和用力肺活量（FVC）等均得到不同程度的改善，治疗组患者较对照组改善更明显（P＜0.05）；治疗组的治疗总有效率为93.9%，显著高于对照组的63.6%（P＜0.05）；两组患者均无不良反应发生，不良反应发生率比较差异无统计学意义（P＞0.05）。结论采用中西医结合治疗矽肺患者安全有效，能显著改善肺功能，提高临床疗效。
목적：탐토중서의결합치료석폐환자적유효성화안전성。방법선취아원수치적65례석폐환자，근거치료방법불동분위대조조33례（구복안다감，항감염화필요시흡양등상규치료）화치료조32례（재상규치료적기출상급여중약“자의극석탕”수전복치료）。비교량조환자적폐공능변화정황、치료총유효솔화불량반응발생솔적차이。결과치료후소유환자적폐활량（VC）、제1초용력호기용적（FEV1）화용력폐활량（FVC）등균득도불동정도적개선，치료조환자교대조조개선경명현（P＜0.05）；치료조적치료총유효솔위93.9%，현저고우대조조적63.6%（P＜0.05）；량조환자균무불량반응발생，불량반응발생솔비교차이무통계학의의（P＞0.05）。결론채용중서의결합치료석폐환자안전유효，능현저개선폐공능，제고림상료효。
Objective To investigate the effect and safety of integrated traditional Chinese and western medicine in the treatment of silicosis. Methods 65 patients with silicosis in our hospital were randomly divided into control group(33 cases,treated with oral theophylline,anti-infective, oxygen and other conventional treatment) and treatment group(32 cases, treated with traditional Chinese medicine"Zinikexi decoction"on the basis of conventional treatment). The pulmonary function changes, total effective rate and adverse reactions rate of two groups were compared. Results After treatment, the VC, FEV1 and FVC of all patients improved in different degrees.Those data of treatment group improved significantly more than control group(P<0.05);The total effective rate of treatment group was 93.9%, which was significantly higher than 63.6%of control group(P<0.05);Both of two patients had no adverse reactions(P>0.05). Conclusion Integrated traditional Chinese and western medicine in the treatment of silicosis is safe and effective.It can significantly improve lung function and clinical outcomes.