中华临床医师杂志(电子版)
中華臨床醫師雜誌(電子版)
중화림상의사잡지(전자판)
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2014年
6期
1143-1146
,共4页
心血管疾病%个体化医疗%全基因组关联研究
心血管疾病%箇體化醫療%全基因組關聯研究
심혈관질병%개체화의료%전기인조관련연구
Cardiovascular diseases%Personalized medicine%Genome-wide association studies
随着人类基因组计划的完成与全基因组关联研究(GWAS)的进展,对性状或疾病的遗传影响因素的认识推动了医疗的个体化进程,个体化医学是对患者个体独有的临床、遗传及环境特性为基础的治疗模式,其诊断治疗及预防决策均是特异的。相信通向个体化医学的剩余难关终将被克服,加强教育并改进体制以适应新的医学方式尤为重要。
隨著人類基因組計劃的完成與全基因組關聯研究(GWAS)的進展,對性狀或疾病的遺傳影響因素的認識推動瞭醫療的箇體化進程,箇體化醫學是對患者箇體獨有的臨床、遺傳及環境特性為基礎的治療模式,其診斷治療及預防決策均是特異的。相信通嚮箇體化醫學的剩餘難關終將被剋服,加彊教育併改進體製以適應新的醫學方式尤為重要。
수착인류기인조계화적완성여전기인조관련연구(GWAS)적진전,대성상혹질병적유전영향인소적인식추동료의료적개체화진정,개체화의학시대환자개체독유적림상、유전급배경특성위기출적치료모식,기진단치료급예방결책균시특이적。상신통향개체화의학적잉여난관종장피극복,가강교육병개진체제이괄응신적의학방식우위중요。
Along with the completion of the Human Genome Project and the development of genome-wide association studies (GWAS), achievements of the genetic determinants of traits or diseases boost the development of personalized medicine,a model based on a patient's unique clinical, genetic, and environmental characteristics, which means that decisions for diagnosis, treatment and prevention are specific to the individual patient. The remaining obstacles to personalized medicine are certain to be overcome, and it is essential that all involved in the application of this new approach to patient care prepare themselves through education and develop system changes as needed.