CAJ | 학술논문

目的：观察慢性阻塞性肺疾病（ COPD ）患者病情与甲状腺素变化的关系。方法分别检测47例COPD急性加重期患者急性加重期和缓解期血清甲状腺素（T4）、游离T4（FT4）、三碘甲状腺原氨酸（T3）、游离T3（FT3）及促甲状腺激素（ TSH）含量，并与对照组比较。结果急性加重期时，COPD组中血清T3、FT3、T4均较对照组显著下降（ P＜0．01）。缓解期时，44例病情缓解者上述指标均明显上升（P＜0．01），病情加重的3例无回升。结论血清甲状腺激素的变化与COPD患者病情严重程度相关，对COPD急性加重期患者的病情判断及预后具有一定的临床参考价值。
목적：관찰만성조새성폐질병（ COPD ）환자병정여갑상선소변화적관계。방법분별검측47례COPD급성가중기환자급성가중기화완해기혈청갑상선소（T4）、유리T4（FT4）、삼전갑상선원안산（T3）、유리T3（FT3）급촉갑상선격소（ TSH）함량，병여대조조비교。결과급성가중기시，COPD조중혈청T3、FT3、T4균교대조조현저하강（ P＜0．01）。완해기시，44례병정완해자상술지표균명현상승（P＜0．01），병정가중적3례무회승。결론혈청갑상선격소적변화여COPD환자병정엄중정도상관，대COPD급성가중기환자적병정판단급예후구유일정적림상삼고개치。
Objective To observe the relationship between thyroid hormones and COPD patients 'conditions .Methods The serum levels of T 3 ,T4 , FT3 , FT4 and TSH of 47 patients with COPD were detected in acute exacerbation stage and remis-sion stage .The results were compared with those of the controls .Results In the acute exacerbation stage ,the serum levels of T3,FT3,T4 in patients with COPD were lower than those of the controls (P<0.01).In the remission stage,the above levels decreased significantly in 44 cases(P<0.01),but did not in 3 severe cases.Conclusion Changes of serum thyroid hormone are correlated with the severity of COPD patients ,which has certain clinical values for the judgment and prognosis of the pa-tients with COPD .