CAJ | 학술논문

目的：分析脑胶质瘤患者的存活、预后影响因素。方法对该院2001～2010年收治的133例脑胶质瘤患者进行回顾性分析，选择患者的性别、年龄、手术前的K PS评分、病理分级、肿瘤长径、手术是否完全切除肿瘤、是否行术后放射治疗等因素进行单因素和多因素分析。结果全组患者中位随访时间36个月，随访率为93％，随访满3年者73例，1、2、3年生存率分别为93％、82％、70％，中位生存时间为62．7个月。多因素回归分析显示病理分级、肿瘤长径、是否行术后放射治疗对生存率有影响。结论高病理分级、肿瘤长径大于或等于6 cm的脑胶质瘤预后不良，手术治疗联合术后放射治疗可以提高脑胶质瘤的远期生存率。
목적：분석뇌효질류환자적존활、예후영향인소。방법대해원2001～2010년수치적133례뇌효질류환자진행회고성분석，선택환자적성별、년령、수술전적K PS평분、병리분급、종류장경、수술시부완전절제종류、시부행술후방사치료등인소진행단인소화다인소분석。결과전조환자중위수방시간36개월，수방솔위93％，수방만3년자73례，1、2、3년생존솔분별위93％、82％、70％，중위생존시간위62．7개월。다인소회귀분석현시병리분급、종류장경、시부행술후방사치료대생존솔유영향。결론고병리분급、종류장경대우혹등우6 cm적뇌효질류예후불량，수술치료연합술후방사치료가이제고뇌효질류적원기생존솔。
Objective To explore the prognosis and related factors of brain glioma .Methods 133 patients who have been con-firmed pathology with brain glioma from Jan .2001 to Dec .2010 were retrospectively analyzed .The factors such as sex ,age ,func-tional status ,histological character ,the longest diameter of tumor ,surgical excision of part or all of the tumor ,whether or not being radiotherapy after surgical excision were selected to evaluate by single factor and multiple factors analysis .Results The median fol-low-up time was 36 months ,The follow-up rate was 93% .73 cases were followed up for 3 years ,the 1- ,2- and 3- year survival rate was 93% ,82% and 70% ,respectively ,the median survival time was 62 .7 months .Multiple factors regression analysis showed that histological character ,the longest diameter of tumor and whether or not being radiotherapy after surgical excision were related to prognosis .Conclusion High-grade of histological character ,the longest diameter of tumor≥6 cm predict poor prognosis ,postop-erative radiotherapy can improve the survival of glioma .