CAJ | 학술논문

目的：了解新生儿及成人ABO血型系统中，A、B、O血型红细胞上A、B、H抗原强度的差异。方法将标准血清倍比稀释，采用试管法检测被测标本红细胞与不同稀释度标准血清的凝集强度直至阴性。将各标本与不同稀释度血清凝集强度计分并累计，最后总积分用SPSS 13．0软件行统计学分析。结果新生儿A、B、H抗原强度均显著低于成人；无论是新生儿还是成人，A抗原的表达强度显著高于B抗原；成年男性与女性之间A、B、H抗原强度无显著差异。结论新生儿与成人之间A、B、H同种抗原强度存在显著差异，抗原种类对A、B、H抗原强度有影响，性别对成人A、B、H抗原强度没有影响。
목적：료해신생인급성인ABO혈형계통중，A、B、O혈형홍세포상A、B、H항원강도적차이。방법장표준혈청배비희석，채용시관법검측피측표본홍세포여불동희석도표준혈청적응집강도직지음성。장각표본여불동희석도혈청응집강도계분병루계，최후총적분용SPSS 13．0연건행통계학분석。결과신생인A、B、H항원강도균현저저우성인；무론시신생인환시성인，A항원적표체강도현저고우B항원；성년남성여녀성지간A、B、H항원강도무현저차이。결론신생인여성인지간A、B、H동충항원강도존재현저차이，항원충류대A、B、H항원강도유영향，성별대성인A、B、H항원강도몰유영향。
Objective To detect the difference of intensity of A ,B ,H antigen on erythrocytes between neonates and adult .Meth-ods Anti-A ,anti-B and anti-H serum were diluted in multiple proportions ,then add the sample erythrocytes into the test tube to react with the serum above .Observe the agglutination between the erythrocytes and the serum ,and score for every agglutination re-action .The total of the score in different dilution of every sample were brought into statistics analysis by SPSS software .Results The A ,B ,H antigen intensity on the surface of erythrocyte of neonates were less than that of adult (P<0 .05) .And no matter neo-nates or adult ,the A antigen intensity on the surface of type A erythrocytes were higher than that of B antigen on the surface of type B erythrocyte(P<0 .05) .The A ,B ,H antigen intensity have no significant difference between adult male and female (P>0 .05) .Conclusion There is a significant difference of A ,B ,H antigen intensity on erythrocytes between neonates and adult .It also can be concluded that the varity of the antigen has effect on intensity of A ,B ,H antigen in erythrocytes ,except sex .