重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2013年
32期
3883-3886
,共4页
陈文海%果磊%王灿%蒲晓姝%魏东山
陳文海%果磊%王燦%蒲曉姝%魏東山
진문해%과뢰%왕찬%포효주%위동산
感染%治疗%慢性感染性创面%创面床准备
感染%治療%慢性感染性創麵%創麵床準備
감염%치료%만성감염성창면%창면상준비
infection%treatment%chronic infective wounds%wound bed preparation
目的:探讨慢性感染性创面的治疗。方法回顾性分析2000~2010年该院收治225例慢性感染性创面患者的临床资料。结果(1)慢性感染性创面以创伤性溃疡、压疮、术后溃疡、糖尿病性溃疡、血管性溃疡为主,占80.4%(181/225)。(2)创面细菌培养阳性率为87.1%(196/225),共培养46种,342株病原菌,革兰阳性菌40.6%(139/342),革兰阴性菌57.6%(197/342),真菌1.8%(6/342),以金黄色葡萄球菌(52株)、大肠埃希菌(43株)、铜绿假单胞属(44株)、肺炎克雷伯(27株)等为主,对青霉素、红霉素、氨苄西林、庆大霉素、复方新诺明等高度耐药,多重耐药率达37.1%(127/342)。从2007年后慢性创面及多重耐药菌呈迅速增加趋势。(3)201例行局部抗菌药物治疗,208例(49例行再手术)行手术封闭创面治疗,213例治愈,12例因经济等原因未愈出院。结论慢性创面感染受多种因素共同影响,注重清创,合理的选择,循环、交替使用抗菌药物以及创面床准备,早期手术封闭创面,能有效控制创面感染,促进创面愈合。
目的:探討慢性感染性創麵的治療。方法迴顧性分析2000~2010年該院收治225例慢性感染性創麵患者的臨床資料。結果(1)慢性感染性創麵以創傷性潰瘍、壓瘡、術後潰瘍、糖尿病性潰瘍、血管性潰瘍為主,佔80.4%(181/225)。(2)創麵細菌培養暘性率為87.1%(196/225),共培養46種,342株病原菌,革蘭暘性菌40.6%(139/342),革蘭陰性菌57.6%(197/342),真菌1.8%(6/342),以金黃色葡萄毬菌(52株)、大腸埃希菌(43株)、銅綠假單胞屬(44株)、肺炎剋雷伯(27株)等為主,對青黴素、紅黴素、氨芐西林、慶大黴素、複方新諾明等高度耐藥,多重耐藥率達37.1%(127/342)。從2007年後慢性創麵及多重耐藥菌呈迅速增加趨勢。(3)201例行跼部抗菌藥物治療,208例(49例行再手術)行手術封閉創麵治療,213例治愈,12例因經濟等原因未愈齣院。結論慢性創麵感染受多種因素共同影響,註重清創,閤理的選擇,循環、交替使用抗菌藥物以及創麵床準備,早期手術封閉創麵,能有效控製創麵感染,促進創麵愈閤。
목적:탐토만성감염성창면적치료。방법회고성분석2000~2010년해원수치225례만성감염성창면환자적림상자료。결과(1)만성감염성창면이창상성궤양、압창、술후궤양、당뇨병성궤양、혈관성궤양위주,점80.4%(181/225)。(2)창면세균배양양성솔위87.1%(196/225),공배양46충,342주병원균,혁란양성균40.6%(139/342),혁란음성균57.6%(197/342),진균1.8%(6/342),이금황색포도구균(52주)、대장애희균(43주)、동록가단포속(44주)、폐염극뢰백(27주)등위주,대청매소、홍매소、안변서림、경대매소、복방신낙명등고도내약,다중내약솔체37.1%(127/342)。종2007년후만성창면급다중내약균정신속증가추세。(3)201례행국부항균약물치료,208례(49례행재수술)행수술봉폐창면치료,213례치유,12례인경제등원인미유출원。결론만성창면감염수다충인소공동영향,주중청창,합리적선택,순배、교체사용항균약물이급창면상준비,조기수술봉폐창면,능유효공제창면감염,촉진창면유합。
Objective To explore the treatment of chronic infective wounds .Methods A retrospective analysis of clinical data in 225 patients were admitted from 2000 to 2010 .Results (1) They were mainly traumatic ulcers ,pressure ulcers ,postoperative ul-cers ,diabetes ulcers ,vascular ulcers in the group ,accounted for 80 .4% (181/225) .(2) Bacterial culture positive rate was 87 .1%(196/225) ,a total of 46 kinds with 342 pathogens were cultured ,gram-positive bacteria 40 .6% (139/342);gram-negative bacteria 57 .6% (197/342);Fungi 1 .8% (6/342) .The main pathogens were S .aureus(52) ,E .coli(43) ,P .aeruginosa(44) ,Klebsiella .SPP (27) ,which were highly resistant to penicillin ,erythromycin ,ampicillin ,gentamicin ,cotrimoxazole and the multidrug resistance rate was 37 .1% (127/342) .Chronic wounds and multidrug resistant bacteria showed rapidly increasing trend from 2007 .(3) 201 pa-tients with topical antibiotic treatment ,208 patients(49 patiens underwent re-operation)underwent operations to close wounds ;213 patiens were recovery ,12 patiens had to leave hospital because economic burden .Conclusion Chronic infective wounds were affect-ed by many factors .emphasizing on debriding ,reasonablechoice ,circulative ,alternate use of antibiotics and wound bed preparation , appling surgery to close wounds in early stage could effectively control wound infection and promote wound healing .