CAJ | 학술논문

　　目的探讨影响冠脉介入术后的急性心肌梗死患者左心室重构的因素。方法选取急性心肌梗死冠脉介入患者125例，在发病72小时内及3个月后行超声心动图检查，根据左室舒张末容量的变化分为心室重构组与无心室重构组。分析N末端B型钠尿肽原（NT-proBNP）、肌钙蛋白I（TnI）、肌酸激酶同工酶MB（CK-MB）、C-反应蛋白（CRP）对心室重构的影响。结果左室重构组与非左室重构组在年龄、性别、吸烟、糖尿病、高血压、高血脂方面无统计学差异。左室重构组CK-MB、TnI水平明显高于非左室重构组（P﹤0.05）；CRP、NT-proBNP水平两组间比较无统计学差异。结论 CK-MB、TnI水平是急性心肌梗死冠脉介入术后左室重构的预测因子。
　　목적탐토영향관맥개입술후적급성심기경사환자좌심실중구적인소。방법선취급성심기경사관맥개입환자125례，재발병72소시내급3개월후행초성심동도검사，근거좌실서장말용량적변화분위심실중구조여무심실중구조。분석N말단B형납뇨태원（NT-proBNP）、기개단백I（TnI）、기산격매동공매MB（CK-MB）、C-반응단백（CRP）대심실중구적영향。결과좌실중구조여비좌실중구조재년령、성별、흡연、당뇨병、고혈압、고혈지방면무통계학차이。좌실중구조CK-MB、TnI수평명현고우비좌실중구조（P﹤0.05）；CRP、NT-proBNP수평량조간비교무통계학차이。결론 CK-MB、TnI수평시급성심기경사관맥개입술후좌실중구적예측인자。
Objective: To investigate the left ventricular remodeling factors in patients with acute myocardial infarction after coronary intervention.Method: A total of 125 patients with acute myocardial infarction(AMI) after coronary intervention were examined by echocardiography within 72 hours of onset and after three months. They were divided into two groups according to extent of progressive left ventricular end-diastolic volume during 3 months. NT-proBNP、TnI、CK-MB、CRP were measured in al patients.Results:The age,gender,smoking,di abetes,hypertension and cholesterol were no significant differences between two groups. The levels of TnI and CK-MB were significantly increased in left ventricular remodeling group(P ﹤ 0.05). The levels of CRP、NT-proBNP were no significant differences between two groups.Conclusion: The levels of TnI and CK-MB were independent predictors of left ventricular remodeling process in patients with AMI after coronary intervention.