中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2013年
5期
531-535
,共5页
近视%青少年%消旋山莨菪碱%渐进多焦点眼镜
近視%青少年%消鏇山莨菪堿%漸進多焦點眼鏡
근시%청소년%소선산랑탕감%점진다초점안경
Myopia%Children%Raceanisodamine%Progressive addition lenses
目的 观察渐进多焦点眼镜联合消旋山莨菪碱滴眼液对减缓青少年中低度近视进展的疗效及安全性.方法 临床病例对照研究.对2010年6月至2011年3月在嵊州市医院眼科诊治的156例中低度近视青少年(8～16周岁)按检查时间随机分成4组,A组为单焦点镜片组；B组为单焦点镜片联合消旋山莨菪碱滴眼液组；C组为渐进多焦点组；D组为渐进多焦点联合消旋山莨菪碱组.于配镜后6月、12月、18月复查屈光度、眼压、眼球前后径、角膜曲率、水平隐斜度,记录患者治疗感受及不良反应.结果 治疗18个月,各组近视屈光度、眼球前后径均有不同程度的增长.各组治疗前后眼压、角膜平均曲率、水平隐斜度差异均无统计学意义(P＞0.05).渐进多焦点眼镜联合消旋山莨菪碱滴眼液组青少年近视屈光度及眼球前后径的增长值不但小于单焦点镜片组,而且小于单用渐进多焦点眼镜组和单焦点镜片联合消旋山莨菪碱滴眼液组,差异有统计学意义(P＜0.05),且未见相关治疗不良反应.结论 渐进多焦点眼镜联合消旋山莨菪碱滴眼液能安全有效地减缓大多数青少年中低度近视的进展.
目的 觀察漸進多焦點眼鏡聯閤消鏇山莨菪堿滴眼液對減緩青少年中低度近視進展的療效及安全性.方法 臨床病例對照研究.對2010年6月至2011年3月在嵊州市醫院眼科診治的156例中低度近視青少年(8～16週歲)按檢查時間隨機分成4組,A組為單焦點鏡片組；B組為單焦點鏡片聯閤消鏇山莨菪堿滴眼液組；C組為漸進多焦點組；D組為漸進多焦點聯閤消鏇山莨菪堿組.于配鏡後6月、12月、18月複查屈光度、眼壓、眼毬前後徑、角膜麯率、水平隱斜度,記錄患者治療感受及不良反應.結果 治療18箇月,各組近視屈光度、眼毬前後徑均有不同程度的增長.各組治療前後眼壓、角膜平均麯率、水平隱斜度差異均無統計學意義(P＞0.05).漸進多焦點眼鏡聯閤消鏇山莨菪堿滴眼液組青少年近視屈光度及眼毬前後徑的增長值不但小于單焦點鏡片組,而且小于單用漸進多焦點眼鏡組和單焦點鏡片聯閤消鏇山莨菪堿滴眼液組,差異有統計學意義(P＜0.05),且未見相關治療不良反應.結論 漸進多焦點眼鏡聯閤消鏇山莨菪堿滴眼液能安全有效地減緩大多數青少年中低度近視的進展.
목적 관찰점진다초점안경연합소선산랑탕감적안액대감완청소년중저도근시진전적료효급안전성.방법 림상병례대조연구.대2010년6월지2011년3월재승주시의원안과진치적156례중저도근시청소년(8～16주세)안검사시간수궤분성4조,A조위단초점경편조；B조위단초점경편연합소선산랑탕감적안액조；C조위점진다초점조；D조위점진다초점연합소선산랑탕감조.우배경후6월、12월、18월복사굴광도、안압、안구전후경、각막곡솔、수평은사도,기록환자치료감수급불량반응.결과 치료18개월,각조근시굴광도、안구전후경균유불동정도적증장.각조치료전후안압、각막평균곡솔、수평은사도차이균무통계학의의(P＞0.05).점진다초점안경연합소선산랑탕감적안액조청소년근시굴광도급안구전후경적증장치불단소우단초점경편조,이차소우단용점진다초점안경조화단초점경편연합소선산랑탕감적안액조,차이유통계학의의(P＜0.05),차미견상관치료불량반응.결론 점진다초점안경연합소선산랑탕감적안액능안전유효지감완대다수청소년중저도근시적진전.
Objective To investigate the effect of progressive addition lenses combined with raceanisodamine on myopia in Chinese juvenile children.Methods A total of 156 case (312 eyes) of 8-16 years-old patients with myopia range from-0.75D ～-5.00D were randomly divided into four groups,in which group A was only treated by monofocal lenses,group B was treated by monofocal lenses and raceanisodamine eye drops,group C was only treated by progressive addition lenses,group D was treated by progressive addition lenses and raceanisodamine eye drops.Refraction,corneal curvature,axial length,intraocular pressure,horizontal phoria was measured in each patient.All the subjects were followed up every 6 months for a period of 18 months.Results After 18 months,the refiaction,anteroposterior axis of eyeball of 4 groups significantly increased comparing with the baseline examination,and corneal curvature,intraocular pressure,horizontal phoria had no significant differences.The increase of refraction,axial length in group D (treated by progressive addition lenses and raceanisodamine eye drops) was significantly less than group A (only treated by monofocal lenses) group B (treated by monofocal lenses and raceanisodamine eye drops) and group C (only treated by progressive addition lenses).There were no other complaints and complications in all subjects.Conclusions The progression of the myopia can be controlled safely and effectively with progressive addition lenses combined with raceanisodamine for most of myopia in Chinese juvenile children.
