CAJ | 학술논문

Chemerin是一种免疫调节因子,在炎性反应相关的一系列蛋白酶作用下可对白细胞产生趋化作用,并参与炎性反应.同时chemerin也是一种调节脂肪细胞生成、代谢及葡萄糖稳态的脂肪因子,其参与了肥胖及代谢综合征的发生、发展.近年来研究发现chemerin对糖尿病及代谢综合征具有一定的诊断意义,且其有可能成为治疗相关疾病的新靶点.
Chemerin시일충면역조절인자,재염성반응상관적일계렬단백매작용하가대백세포산생추화작용,병삼여염성반응.동시chemerin야시일충조절지방세포생성、대사급포도당은태적지방인자,기삼여료비반급대사종합정적발생、발전.근년래연구발현chemerin대당뇨병급대사종합정구유일정적진단의의,차기유가능성위치료상관질병적신파점.
Chemerin is an immunomodulating factor which is processed by a variety of proteases linked to inflammation to induce chemotaxis in leukocyte.Meanwhile,chemerin is a novel adipokine that regulates adipocyte development and metabolic function as well as glucose homeostasis,and takes part in the occurrence and development of obesity and metabolic syndrome.Recent years,studies show that chemerin may be helpful for diagnosis of diabetes and metabolic syndrome,and it may become a new target for the treatment of related disorders.