CAJ | 학술논문

目的探讨原发性前列腺移行细胞癌的诊断与治疗方法,为早期准确发现并治疗提供线索.方法回顾性分析3例原发性前列腺移行细胞癌的临床资料.结果 3例病例均可诊断为原发性前列腺癌,2例发现时已是晚期病变,术前检查(血清前列腺特异性抗原、B超等)均未能准确提示其诊断.术后病理原发性前列腺癌诊断明确,术后1例失随访,1例早期病变应用吡柔比星灌注后随访17个月后情况良好.1例晚期术后2个月复查腰椎MRI发现骨转移.结论本病早期诊断困难,确诊主要需行经直肠B超引导下前列腺穿刺活检或尿道镜检并取病理组织检查,因其预后较差,且容易病理漏诊或误诊,需排除多中心病变及混合肿瘤情况而选择治疗方式.
목적 탐토원발성전렬선이행세포암적진단여치료방법,위조기준학발현병치료제공선색.방법 회고성분석3례원발성전렬선이행세포암적림상자료.결과 3례병례균가진단위원발성전렬선암,2례발현시이시만기병변,술전검사(혈청전렬선특이성항원、B초등)균미능준학제시기진단.술후병리원발성전렬선암진단명학,술후1례실수방,1례조기병변응용필유비성관주후수방17개월후정황량호.1례만기술후2개월복사요추MRI발현골전이.결론 본병조기진단곤난,학진주요수행경직장B초인도하전렬선천자활검혹뇨도경검병취병리조직검사,인기예후교차,차용역병리루진혹오진,수배제다중심병변급혼합종류정황이선택치료방식.
Objective To explore the experience in diagnosis and treatment ot primary transitional cell carcinoma of prostate for the early and accurate to diagnosis and treatment.Methods The clinical data and features of 3 cases were retrospectively reviewed.Results All patients were diagnosed as primary transitional cell carcinoma of prostate.Two cases were advanced tumor.The preoperative examinations (ultrasound and serum,PSA) have failed to accurately indicate the diagnosis.All of them were confirmed by pathological examination.1 case lost follow-up,1 case performed TURP + chemotherapy through intravesical administration have survived 17 months respectively till today.The other case has already survived 2 months postoperatively but with lumbar spine bone metastasis.Conclusions Early diagnosis of primary transitional cell carcinoma of prostate is difficult.The diagnosis of the disease depends on the transrectal needle biopsy of the prostate or the specimens of the prostate after the Urethroscopy.Because of the prognosis is bad,and prone to pathological missed diagnosis or misdiagnosis.Need to exclude multicentric lesions and mixed tumor and choice of treatment method.