CAJ | 학술논문

目的：探讨不同孕周开始治疗的妊娠梅毒患者的妊娠结局，为不同孕周开始治疗的妊娠梅毒患者提供治疗依据。方法对我院53例妊娠梅毒患者按确诊并开始治疗的不同孕周分为＜16孕周与≥16孕周两组，观察两组妊娠结局与新生儿素质等情况。结果①＜16孕周组28例，正常足月分娩27例（96.4%），≥16孕周25例，正常足月分娩13例（52%），两组结果具有显著性差异（P＜0.01）；②新生儿阿氏评分，＜16孕周组平均8.75分，≥16孕周组平均6.96分（P＜0.05）；③新生儿体重：＜16孕周组平均3.21 kg，≥16孕周组平均2.76 kg（P＜0.05)。结论16孕周前确诊并开始治疗的妊娠梅毒患者，通过正规驱梅治疗，其胎儿相对安全；16孕周后确诊并开始治疗的妊娠梅毒患者其妊娠风险很大。
목적：탐토불동잉주개시치료적임신매독환자적임신결국，위불동잉주개시치료적임신매독환자제공치료의거。방법대아원53례임신매독환자안학진병개시치료적불동잉주분위＜16잉주여≥16잉주량조，관찰량조임신결국여신생인소질등정황。결과①＜16잉주조28례，정상족월분면27례（96.4%），≥16잉주25례，정상족월분면13례（52%），량조결과구유현저성차이（P＜0.01）；②신생인아씨평분，＜16잉주조평균8.75분，≥16잉주조평균6.96분（P＜0.05）；③신생인체중：＜16잉주조평균3.21 kg，≥16잉주조평균2.76 kg（P＜0.05)。결론16잉주전학진병개시치료적임신매독환자，통과정규구매치료，기태인상대안전；16잉주후학진병개시치료적임신매독환자기임신풍험흔대。
Objective To explore the pregnancy outcomes of pregnant syphilis patients treated in different pregnant weeks and provide a treatment referrence for pregnant syphilis patients. Methods 53 cases of pregnant patients with syphilis were divided into two groups according to the primary treatment time point:pregnant periods≥16 weeks and<16 weeks, the pregnancy outcomes and neonatal body build of two groups patients were traced and analyzed. Results 27 cases of which 28 cases pregnant syphilis patients maturely deliverd with enough month (96.4%) in the group<16 gestational weeks. But only 13 cases of 25 cases patients in the other group≥16 gestational weeks did it (52%). The differences between the two group's data were signiifcant (P<0.05). The neonatal apgar scoring showed the group<16 weeks averaged 8.75 scores, the other one≥16 weeks 6.96 scores (P<0.05). The neonatal weight:the average weights were 3.21 kilograms (<16 weeks) and 2.76 kilograms (≥16 weeks) respectively (P<0.05). Conclusion The pregnant syphilis patients were deifnitely diagnosed and received treatment before 16 gestational weeks, the fetals survival was safe relatively by regular anti-syphilis therapy, meaningwhile the pregnancy outcomes will burdened a very high risk factor after 16 weeks.