国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
22期
3455-3458
,共4页
陈霞%黄鸣剑%陈少藩%王建彬
陳霞%黃鳴劍%陳少藩%王建彬
진하%황명검%진소번%왕건빈
新生儿高胆红素血症%胆红素脑病%病因%早发现和早治疗
新生兒高膽紅素血癥%膽紅素腦病%病因%早髮現和早治療
신생인고담홍소혈증%담홍소뇌병%병인%조발현화조치료
Neonatal hyperbilirubinemia%Bilirubin encephalopathy%Etiology%Early detection and early treatment
目的 分析新生儿高胆红素血症的高危因素,建立重点监测、及早发现和早治疗病理性黄疸的方法,减少胆红素脑病的发生.方法 选取2012年5月至2013年4月我院新生儿科收治的471例新生儿高胆红素血症患儿,回顾性分析新生儿高胆红素血症的病因和3例胆红素脑病的临床资料.结果 本研究中,新生儿高胆红素血症已明确病因的排位依次是围生因素(54.99％)、血液系统方面的原因(12.74％)、感染(4.46％)；3例胆红素脑病的病因无一例是溶血性疾病,与围生因素和家长不重视有关.结论 新生儿黄疸是新生儿期常见的疾病,14.52％患新生儿高胆红素血症(这个比例比实际低),不及时治疗会发生胆红素脑病,留下后遗症,影响预后.从孕期开始对家长进行黄疸知识的普及,新生儿科医生进驻爱婴区查房,对存在高危因素的婴儿重点监测,对出院病人动态随访,是早期发现新生儿高胆红素血症和预防胆红素脑病的最有效预防干预措施；对高胆红素血症应尽早采取首选光疗加药物辅助治疗的综合方法,减少胆红素脑病的发生.
目的 分析新生兒高膽紅素血癥的高危因素,建立重點鑑測、及早髮現和早治療病理性黃疸的方法,減少膽紅素腦病的髮生.方法 選取2012年5月至2013年4月我院新生兒科收治的471例新生兒高膽紅素血癥患兒,迴顧性分析新生兒高膽紅素血癥的病因和3例膽紅素腦病的臨床資料.結果 本研究中,新生兒高膽紅素血癥已明確病因的排位依次是圍生因素(54.99％)、血液繫統方麵的原因(12.74％)、感染(4.46％)；3例膽紅素腦病的病因無一例是溶血性疾病,與圍生因素和傢長不重視有關.結論 新生兒黃疸是新生兒期常見的疾病,14.52％患新生兒高膽紅素血癥(這箇比例比實際低),不及時治療會髮生膽紅素腦病,留下後遺癥,影響預後.從孕期開始對傢長進行黃疸知識的普及,新生兒科醫生進駐愛嬰區查房,對存在高危因素的嬰兒重點鑑測,對齣院病人動態隨訪,是早期髮現新生兒高膽紅素血癥和預防膽紅素腦病的最有效預防榦預措施；對高膽紅素血癥應儘早採取首選光療加藥物輔助治療的綜閤方法,減少膽紅素腦病的髮生.
목적 분석신생인고담홍소혈증적고위인소,건립중점감측、급조발현화조치료병이성황달적방법,감소담홍소뇌병적발생.방법 선취2012년5월지2013년4월아원신생인과수치적471례신생인고담홍소혈증환인,회고성분석신생인고담홍소혈증적병인화3례담홍소뇌병적림상자료.결과 본연구중,신생인고담홍소혈증이명학병인적배위의차시위생인소(54.99％)、혈액계통방면적원인(12.74％)、감염(4.46％)；3례담홍소뇌병적병인무일례시용혈성질병,여위생인소화가장불중시유관.결론 신생인황달시신생인기상견적질병,14.52％환신생인고담홍소혈증(저개비례비실제저),불급시치료회발생담홍소뇌병,류하후유증,영향예후.종잉기개시대가장진행황달지식적보급,신생인과의생진주애영구사방,대존재고위인소적영인중점감측,대출원병인동태수방,시조기발현신생인고담홍소혈증화예방담홍소뇌병적최유효예방간예조시；대고담홍소혈증응진조채취수선광료가약물보조치료적종합방법,감소담홍소뇌병적발생.
Objective To analyze risk factors of neonatal hyperbilirubinemia,to find a way of giving special supervision,early detection and early treatment of pathological jaundice,to reduce the occurrence of bilirubin encephalopathy.Methods We chose 471 cases of neonatal hyperbilirubinemia admitted in Neonatology Department of our hospital from May 2012 to April 2013 as the research objects,a retrospectively analysis was carried out for the cause of neonatal hyperbilirubinemia and the clinical data of 3 cases of bilirubin encephalopathy.Results In this study,perinatal factors were the most important clear etiology of neonatal hyperbilirubinemia,accounting for 54.99％,followed by blood system reasons,accounting for 12.74％,the third etiology was the infection,accounting for 4.46％; in 3 cases of bilirubin encephalopathy,none of them were caused by hemolytic disease,in fact,it was relevant to the perinatal factors and the parents' ignorance.Conclusion Neonatal jaundice was a common disease of infants.14.52％ of them had neonatal hyperbilirubinemia (this proportion was lower than the actual),if we do not treat the disease in time,it will cause sequel and have influence on the prognosis.The most effective ways to discover neonatal hyperbilirubinemia and prevent bilirubin encephalopathy are:popularization of the jaundice knowledge from pregnancy for new parents,ward rounds of pediatrician in baby area,special supervision for the infants with risk factors of neonatal hyperbilirubinemia,dynamic follow-up to discharged patients; to reduce the occurrence of bilirubin encephalopathy,those of neonatal hyperbilirubinemia should be suggested to adopt the treatment of phototherapy and drug as early as possible.
