当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2013年
18期
51-52
,共2页
氢氯噻嗪%左旋氨氯地平%老年原发性高血压
氫氯噻嗪%左鏇氨氯地平%老年原髮性高血壓
경록새진%좌선안록지평%노년원발성고혈압
Elderly essential hypertension%Hydrochlorothiazide%L-amlodipine
目的观察小剂量氢氯噻嗪联合左旋氨氯地平治疗老年原发性高血压的临床疗效。方法将90例老年原发性高血压患者随机分为治疗组（氢氯噻嗪联合左旋氨氯地平）和对照组（单用左旋氨氯地平），各45例，疗程8周。结果两组总有效率比较，差异无统计学意义(P＞0.05)，但显效率治疗组优于对照组，差异有统计学意义（P＜0.05）。治疗2、4、8周后治疗组患者SBP、DBP平均下降均优于对照组，差异有统计学意义（P＜0.05）。两组治疗前后血生化指标未见明显异常，差异无统计学意义(P＞0.05)。结论小剂量氢氯噻嗪联合左旋氨氯地平治疗老年原发性高血压，起效快且疗效显著，优于单用左旋氨氯地平。
目的觀察小劑量氫氯噻嗪聯閤左鏇氨氯地平治療老年原髮性高血壓的臨床療效。方法將90例老年原髮性高血壓患者隨機分為治療組（氫氯噻嗪聯閤左鏇氨氯地平）和對照組（單用左鏇氨氯地平），各45例，療程8週。結果兩組總有效率比較，差異無統計學意義(P＞0.05)，但顯效率治療組優于對照組，差異有統計學意義（P＜0.05）。治療2、4、8週後治療組患者SBP、DBP平均下降均優于對照組，差異有統計學意義（P＜0.05）。兩組治療前後血生化指標未見明顯異常，差異無統計學意義(P＞0.05)。結論小劑量氫氯噻嗪聯閤左鏇氨氯地平治療老年原髮性高血壓，起效快且療效顯著，優于單用左鏇氨氯地平。
목적관찰소제량경록새진연합좌선안록지평치료노년원발성고혈압적림상료효。방법장90례노년원발성고혈압환자수궤분위치료조（경록새진연합좌선안록지평）화대조조（단용좌선안록지평），각45례，료정8주。결과량조총유효솔비교，차이무통계학의의(P＞0.05)，단현효솔치료조우우대조조，차이유통계학의의（P＜0.05）。치료2、4、8주후치료조환자SBP、DBP평균하강균우우대조조，차이유통계학의의（P＜0.05）。량조치료전후혈생화지표미견명현이상，차이무통계학의의(P＞0.05)。결론소제량경록새진연합좌선안록지평치료노년원발성고혈압，기효쾌차료효현저，우우단용좌선안록지평。
Objective To investigate the effects of treatment of elderly essential hypertension by low-dose hydrochlorothiazide combining with L-amlodipine.Methods 90 patients were randomly divided into the treatment group treated by low-dose hydrochlorothiazide combining with L-amlodipine and the control group treated by L-amlodipine.All of the two groups'course were 8 weeks.Results Total effective rate of the two groups is not obvious different(P>0.05),but the obvious effective rate of the treatment group is superior to that of the control group(P<0.05),and the biochemical indexs of the two groups are not obvious different between pre and post treatment(P>0.05).Conclusion The efficacy of the control group is superior to that of the control group.
