CAJ | 학술논문

目的探讨残胃癌（GSC）临床病理特征及影响生存预后的因素。方法追踪并随访中山大学附属第一医院1998年1月至2010年2月的49例GSC患者，分析其临床病理特征及可能影响生存的因素。结果收集有效GSC病例41例（男37例，90.24%），中位发病年龄66岁，初次手术至GSC发生的平均病程为25年，且随年龄的增长有缩短趋势（P =0.003）；患者年龄越小， GSC的病理分期越高（P <0.01），组织分化程度越低；多数GSC伴淋巴结的转移（60.98%），5年生存率37.00%。Cox比例风险模型生存分析显示，临床病理分期对生存预后的影响有统计学意义（P =0.004）。结论残胃癌是病理类型相对特殊的一类胃癌，手术根治是提高残胃癌生存预后的关键。
목적탐토잔위암（GSC）림상병리특정급영향생존예후적인소。방법추종병수방중산대학부속제일의원1998년1월지2010년2월적49례GSC환자，분석기림상병리특정급가능영향생존적인소。결과수집유효GSC병례41례（남37례，90.24%），중위발병년령66세，초차수술지GSC발생적평균병정위25년，차수년령적증장유축단추세（P =0.003）；환자년령월소， GSC적병리분기월고（P <0.01），조직분화정도월저；다수GSC반림파결적전이（60.98%），5년생존솔37.00%。Cox비례풍험모형생존분석현시，림상병리분기대생존예후적영향유통계학의의（P =0.004）。결론잔위암시병리류형상대특수적일류위암，수술근치시제고잔위암생존예후적관건。
Objective To study the clinical feature and prognosis of gastric stump carcinoma (GSC). Methods A retrospective study was performed by following GSC cases diagnosed at the First Affiliated Hospital of Sun Yat-sen University between January, 1998 and February, 2010. The clinical feature and potential prognostic factors were analyzed. Results Forty-one GSC cases (male 37, 90.24%) were collected, with a 66-year median age, and an average 25-year interval between primary operation and GSC occurrence, which was negatively correlated with aging (P = 0.003). The younger of GSC patients, the higher of pathological stages and the lower of the differentiation degrees (P =0.004). Most GSC was complicated with lymph nodes metastasis (60.98%). The 5-year survival rate was 37.00%. Cox proportional hazards model for survival analysis indicated that the clinical-pathological stage significantly affected survival and prognosis. Conclusion Regular gastroscopy is important to improve the quality of life in patients accepted subtotal gastrectomy.