中国药物应用与监测
中國藥物應用與鑑測
중국약물응용여감측
CHINESE JOURNAL OF DRUG APPLICATION AND MONITORING
2013年
3期
183-184
,共2页
斑蝥酸钠注射液%喉头水肿%药品不良反应
斑蝥痠鈉註射液%喉頭水腫%藥品不良反應
반모산납주사액%후두수종%약품불량반응
Disodium cantharidinate injection%Laryngeal edema%Adverse drug reaction
1例72岁男性患者,确诊为左肺腺癌7个月,既往有小牛血清去蛋白过敏史。治疗期间输入斑蝥酸钠注射液约30 min,患者突然烦躁,急发憋闷、喉痒、发声嘶哑、吸气性呼吸困难,口唇明显发绀,三凹征阳性等。立即停止输入,给予氧气吸入,甲强龙、异丙嗪、葡萄糖酸钙抗过敏以及其他对症治疗,约20 min后,患者症状明显改善,口唇发绀及三凹征消失。
1例72歲男性患者,確診為左肺腺癌7箇月,既往有小牛血清去蛋白過敏史。治療期間輸入斑蝥痠鈉註射液約30 min,患者突然煩躁,急髮憋悶、喉癢、髮聲嘶啞、吸氣性呼吸睏難,口脣明顯髮紺,三凹徵暘性等。立即停止輸入,給予氧氣吸入,甲彊龍、異丙嗪、葡萄糖痠鈣抗過敏以及其他對癥治療,約20 min後,患者癥狀明顯改善,口脣髮紺及三凹徵消失。
1례72세남성환자,학진위좌폐선암7개월,기왕유소우혈청거단백과민사。치료기간수입반모산납주사액약30 min,환자돌연번조,급발별민、후양、발성시아、흡기성호흡곤난,구진명현발감,삼요정양성등。립즉정지수입,급여양기흡입,갑강룡、이병진、포도당산개항과민이급기타대증치료,약20 min후,환자증상명현개선,구진발감급삼요정소실。
One 72-year-old male patient was diagnosed with left lung adenocarcinoma 7 months ago. He had a history of deproteinised calf blood serum injection allergy. About 30 minutes after the disodium cantharidinate injection was used, the patient suddenly developed dysphoria, oppressed, throat itching, voice hoarse, inspiratory dyspnea, obvious lips hematocyanosis, three depression sign positive and so on. This medicine was immediately stopped. The patient received oxygen inhalation and the therapy of antianaphylaxis by methylprednisolone, promethazine hydrochloride injection, calcium gluconate and other treatments. After about 20 minutes, the symptoms improved obviously, lips hematocyanosis and three depression sign disappeared.