影像诊断与介入放射学
影像診斷與介入放射學
영상진단여개입방사학
JOURNAL OF DIAGNOSTIC IMAGING AND INTERVENTIONAL RADIOLOGY
2013年
3期
36-40
,共5页
陈美容%罗学毛%刘壮盛%钟向阳%吴标
陳美容%囉學毛%劉壯盛%鐘嚮暘%吳標
진미용%라학모%류장성%종향양%오표
DCE-MRI%1H-MRS%乳腺良恶性病变%鉴别诊断
DCE-MRI%1H-MRS%乳腺良噁性病變%鑒彆診斷
DCE-MRI%1H-MRS%유선량악성병변%감별진단
Dynamic contrast-enhanced MRI%1H-MRS%Benign and malignant breast lesions%Differential diagnosis
目的探讨磁共振动态增强(DCE-MRI)和质子波谱成像(1H MRS)对乳腺良恶性病变的诊断价值。方法对乳腺钼靶或超声检查发现的63例女性患者共计83个乳腺病灶行DCE-MR检查,选取其中58个病灶行1H-MRS检查。分析增强后病灶的形态学表现和时间—信号强度曲线;观察胆碱峰的情况。所有病灶在MR检查后均行手术或穿刺活检。结果病理证实行DCE-MR检查的83个病灶中,恶性病变46个,良性病变37个;行1H-MRS检查的58个病灶中恶性病变32个,良性病变26个。形态学表现诊断乳腺良恶性病变的敏感性为73.9%(34/46),特异性为94.6%(35/37),准确性为85.5%(71/83);时间—信号强度曲线的敏感性为93.5%(43/46),特异性为73.0%(35/37),准确性为84.3%(70/83);1H-MRS敏感性65.6%(21/32),特异性为84.6%(22/26),准确性为74.1%(43/58)。形态学表现的特异性最高,敏感性较低;时间—信号强度曲线的敏感性最高,特异性最低;1H-MRS的敏感性最低,特异性较高;3者诊断的准确性无显著差别。结论磁共振动态增强可鉴别乳腺良恶性病变,形态学表现应结合时间—信号强度曲线综合分析,必要时可联合波谱成像提高其特异性。
目的探討磁共振動態增彊(DCE-MRI)和質子波譜成像(1H MRS)對乳腺良噁性病變的診斷價值。方法對乳腺鉬靶或超聲檢查髮現的63例女性患者共計83箇乳腺病竈行DCE-MR檢查,選取其中58箇病竈行1H-MRS檢查。分析增彊後病竈的形態學錶現和時間—信號彊度麯線;觀察膽堿峰的情況。所有病竈在MR檢查後均行手術或穿刺活檢。結果病理證實行DCE-MR檢查的83箇病竈中,噁性病變46箇,良性病變37箇;行1H-MRS檢查的58箇病竈中噁性病變32箇,良性病變26箇。形態學錶現診斷乳腺良噁性病變的敏感性為73.9%(34/46),特異性為94.6%(35/37),準確性為85.5%(71/83);時間—信號彊度麯線的敏感性為93.5%(43/46),特異性為73.0%(35/37),準確性為84.3%(70/83);1H-MRS敏感性65.6%(21/32),特異性為84.6%(22/26),準確性為74.1%(43/58)。形態學錶現的特異性最高,敏感性較低;時間—信號彊度麯線的敏感性最高,特異性最低;1H-MRS的敏感性最低,特異性較高;3者診斷的準確性無顯著差彆。結論磁共振動態增彊可鑒彆乳腺良噁性病變,形態學錶現應結閤時間—信號彊度麯線綜閤分析,必要時可聯閤波譜成像提高其特異性。
목적탐토자공진동태증강(DCE-MRI)화질자파보성상(1H MRS)대유선량악성병변적진단개치。방법대유선목파혹초성검사발현적63례녀성환자공계83개유선병조행DCE-MR검사,선취기중58개병조행1H-MRS검사。분석증강후병조적형태학표현화시간—신호강도곡선;관찰담감봉적정황。소유병조재MR검사후균행수술혹천자활검。결과병리증실행DCE-MR검사적83개병조중,악성병변46개,량성병변37개;행1H-MRS검사적58개병조중악성병변32개,량성병변26개。형태학표현진단유선량악성병변적민감성위73.9%(34/46),특이성위94.6%(35/37),준학성위85.5%(71/83);시간—신호강도곡선적민감성위93.5%(43/46),특이성위73.0%(35/37),준학성위84.3%(70/83);1H-MRS민감성65.6%(21/32),특이성위84.6%(22/26),준학성위74.1%(43/58)。형태학표현적특이성최고,민감성교저;시간—신호강도곡선적민감성최고,특이성최저;1H-MRS적민감성최저,특이성교고;3자진단적준학성무현저차별。결론자공진동태증강가감별유선량악성병변,형태학표현응결합시간—신호강도곡선종합분석,필요시가연합파보성상제고기특이성。
@@@@Objective To compare dynamic contrast-enhanced(DCE)MRI and proton spectroscopy(1H-MRS)for differentiating benign from malignant breast lesions.Methods 63 women with 83 suspicious breast lesions seen on mammography or ultrasound examinations underwent DCE MRI. 58 breast lesions were also examined with 1H-MRS. The MR findings were compared with histology.Results Of 83 lesions on DCE MRI,46 were malignant and 37 benign. Of 58 lesions on 1H-MRS,32 were malignant and 26 were benign.The sensitivities,specificities and accuracy of morphological diagnosis were 73.9%(34/46),94.6%(35/37), 85.5%(71/83),respectively without significant difference from those of time signal intensity curves [93.5%(43/46),73%(35/37), 84.3%(70/83)] and those of MRS [65.6%(21/32),84.6%(22/26),74.1%(43/58)].Conclusions DCE MRI has high sensitivity for differentiating benign from malignant breast lesions. The specificity and accuracy can be improved by integrating with morphological features and MRS.