CAJ | 학술논문

目的探讨神经纤维瘤病Ⅱ型（NF2）中颅神经受累的MR表现。方法23例NF2患者均行头颅常规MR平扫及3D-FLASH增强扫描，MRI上颅神经增粗或形成结节作为颅神经受累标准，按12对颅神经根颅内段解剖路径观察和统计颅神经受累情况。结果23例12对颅神经受累情况如下：Ⅰ（嗅）神经1例（4.3%，单侧）、Ⅱ（视）神经0例，Ⅲ（动眼）神经7例（30.4%，单侧4例，双侧3例）、Ⅳ（滑车神经）1例（4.3%，单侧）、Ⅴ（三叉神经）15例（65.2%，单侧5例，双侧10例）、Ⅵ（外展神经）1例（4.3%，单侧受累）、Ⅶ（面神经）5例（21.7%，单侧4例，双侧1例）、Ⅷ（听神经）23例（100%，单侧5例，双侧18例）、Ⅸ/Ⅹ/Ⅺ（舌咽/迷走/副神经）受累9例（39.1%，单侧3例，双侧6例）、Ⅻ（舌下神经）6例（26.1%，单侧3例，双侧3例）结论NF2除了累及听神经外，常累及视神经以外的其他颅神经，诊断时应沿颅神经路径进行观察，以防漏诊。
목적탐토신경섬유류병Ⅱ형（NF2）중로신경수루적MR표현。방법23례NF2환자균행두로상규MR평소급3D-FLASH증강소묘，MRI상로신경증조혹형성결절작위로신경수루표준，안12대로신경근로내단해부로경관찰화통계로신경수루정황。결과23례12대로신경수루정황여하：Ⅰ（후）신경1례（4.3%，단측）、Ⅱ（시）신경0례，Ⅲ（동안）신경7례（30.4%，단측4례，쌍측3례）、Ⅳ（활차신경）1례（4.3%，단측）、Ⅴ（삼차신경）15례（65.2%，단측5례，쌍측10례）、Ⅵ（외전신경）1례（4.3%，단측수루）、Ⅶ（면신경）5례（21.7%，단측4례，쌍측1례）、Ⅷ（은신경）23례（100%，단측5례，쌍측18례）、Ⅸ/Ⅹ/Ⅺ（설인/미주/부신경）수루9례（39.1%，단측3례，쌍측6례）、Ⅻ（설하신경）6례（26.1%，단측3례，쌍측3례）결론NF2제료루급은신경외，상루급시신경이외적기타로신경，진단시응연로신경로경진행관찰，이방루진。
@@@@Objective To investigate cranial nerve involvement of type II neurofibromatosis(NF2).Methods Twenty-three NF2 patients underwent conventional and contrast-enhanced 3D-FLASH MRI.Cranial nerve involvement was diagnosed when thickening or nodule was observed in the cranial nerve.Results Cranial nerve involvement of the 23 patients included unilateral olfactory schwannoma(1/23,4.3%),unilateral(4)or bilateral(3)oculomotor nerve schwannomas(7/23,30.4%),unilateral trochlear schwannoma(1/23,4.3%),unilateral(5)or bilateral(10)trigeminal schwannomas(15/23,65.2%),unilateral abducens schwannoma (1/23,4.3%),unilateral(4)or bilateral(1)facial nerve schwannomas(5/23,21.7%),unilateral(5)or bilateral(18)vestibular schwannomas(23/23,100%),unilateral(3)or bilateral(6)glossopharyngeal ,vagal,or accessory schwannomas(9/23,39.1%),and unilateral(3)or bilateral(3)hypoglossal schwannomas(6/23,26.1%).Conclusions In addition to universal involvement of the auditory nerve,NF2 often involved other cranial nerves except for the optic nerve.The path of the cranial nerves should be carefully inspected on MRI.