CAJ | 학술논문

酌-聚谷氨酸是一种由微生物发酵制备的氨基酸多聚物，主链上有很多游离羧基基团，易于修饰和交联。用酌-聚谷氨酸制得的水凝胶属于可降解的环境友好型水凝胶，具有生物相容性、细胞安全性、较好的溶胀性和 pH敏感性等优点，在环境保护和生物医药方面有广泛的应用。综述了近年来酌-聚谷氨酸水凝胶的物理和化学制备方法以及应用研究进展，并对其未来发展进行了展望。
작-취곡안산시일충유미생물발효제비적안기산다취물，주련상유흔다유리최기기단，역우수식화교련。용작-취곡안산제득적수응효속우가강해적배경우호형수응효，구유생물상용성、세포안전성、교호적용창성화 pH민감성등우점，재배경보호화생물의약방면유엄범적응용。종술료근년래작-취곡안산수응효적물리화화학제비방법이급응용연구진전，병대기미래발전진행료전망。
Poly (γ-glutamic acid) (γ-PGA) is an amino acid polymer produced by Bacillus subtilis with many free carboxyl groups in the main chain,and can be modified and crosslinked easily.The hydrogels prepared from γ-PGA are biodegradable and environment -friendly hydrogels with biocompatibility and cell security,and it was applied widely in the areas of environmental protection and biomedicine.Recent progress of the preparations,by the physical and chemical methods,and applications were summarized.Their developments in the future were predicted.