CAJ | 학술논문

目的探讨脂蛋白α检测对糖尿病足诊断的价值。方法以我院2009年1月-2012年12月间27例糖尿病足病患者为研究对象，将27例未患有糖尿病足病的糖尿病患者作为对照，比较两组患者在糖尿病相关生化指标和糖尿病足病相关脂蛋白指标间的差异。结果两组患者在TG、TC、HEL-C、LDL-C、FPG、ApoA、ApoB、ApoE含量方面无显著差异，观察组脂蛋白α浓度高于对照组，差异有统计学意义(P <0.05)。在Logistic多因素回归分析中，对糖尿病患者是否发生糖尿病足病有较为显著的影响是患者的性别、糖尿病病程及脂蛋白α的含量。结论脂蛋白α可以作为糖尿病足病诊断的重要指标。
목적탐토지단백α검측대당뇨병족진단적개치。방법이아원2009년1월-2012년12월간27례당뇨병족병환자위연구대상，장27례미환유당뇨병족병적당뇨병환자작위대조，비교량조환자재당뇨병상관생화지표화당뇨병족병상관지단백지표간적차이。결과량조환자재TG、TC、HEL-C、LDL-C、FPG、ApoA、ApoB、ApoE함량방면무현저차이，관찰조지단백α농도고우대조조，차이유통계학의의(P <0.05)。재Logistic다인소회귀분석중，대당뇨병환자시부발생당뇨병족병유교위현저적영향시환자적성별、당뇨병병정급지단백α적함량。결론지단백α가이작위당뇨병족병진단적중요지표。
Objective To analysis the effect of lipoprotein α in the diagnosis of diabetic foot. Methods 27 cases with diabetic foot were in the study as the objective group, and 27 cases without diabetic foot were in the study as the control group. The difference of the diabetes related biochemical indicators and diabetic foot disease related indicators were compared. Result There was no significant difference between the two groups except the lipoprotein α. In the logistic regression analysis, the sex, the time diabetes duration and the level of lipoprotein α had a significant relationship with the diabetic foot. Conclusion It would get a satisfactory effect to use lipoprotein α as a predictor in the diagnosis of Diabetic foot.