CAJ | 학술논문

目的观察加巴喷丁联合阿米替林治疗神经病理性疼痛的临床疗效。方法将90例神经病理性疼痛患者分为观察组48例、对照组42例，分别给予加巴喷丁联合阿米替林治疗4周和单纯应用加巴喷丁治疗4周。采用VAS评分方法评估疗效，观察不良反应发生率。结果观察组有效率显著高于对照组、不良反应率显著低于对照组，差异有统计学意义(P <0.05)。与对照组比较，观察组治疗后VAS评分明显下降，差异有统计学意义(P <0.05)。结论加巴喷丁联合阿米替林治疗神经病理性疼痛安全有效。
목적관찰가파분정연합아미체림치료신경병이성동통적림상료효。방법장90례신경병이성동통환자분위관찰조48례、대조조42례，분별급여가파분정연합아미체림치료4주화단순응용가파분정치료4주。채용VAS평분방법평고료효，관찰불량반응발생솔。결과관찰조유효솔현저고우대조조、불량반응솔현저저우대조조，차이유통계학의의(P <0.05)。여대조조비교，관찰조치료후VAS평분명현하강，차이유통계학의의(P <0.05)。결론가파분정연합아미체림치료신경병이성동통안전유효。
Objective Using gabapentin combined with amitriptyline in the treatment of neuropathic pain, to observe its clinical curative effect. Methods Patients with neuropathic pain in 48 cases for the observation group, with gabapentin combined with amitriptyline for 4 weeks; 42 patients with neurogenic pathological pain for the control group, the simple application of gabapentin in the treatment of 4 weeks. Evaluation of the curative effect of using VAS scoring method, observe the incidence rate of adverse reaction. Results In the observation group was significantly higher than that in the control group, the adverse reaction rate was significantly lower than the control group, the difference was statistically significant(P <0.05). Compared with the control group, VAS score decreased significantly after treatment, the difference was statistically significant(P <0.05). Conclusion Gabapentin combined with amitriptyline in the treatment of neuropathic pain is safe and effective.