中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
13期
8-10
,共3页
急性心肌梗死%D-二聚体%肌钙蛋白I%诊断
急性心肌梗死%D-二聚體%肌鈣蛋白I%診斷
급성심기경사%D-이취체%기개단백I%진단
Acute myocardial infarction%D-Dimer%cTnI%Diagnosis
目的探讨D-二聚体（DD）和心肌肌钙蛋白I（cTnI）联合检测在急性心肌梗死（AMI）早期诊断中的临床价值。方法对47例AMI患者（观察组）及41例非心血管疾病患者（对照组）采血进行DD及cTnI定性测定并比较。结果观察组DD及cTnI检测阳性率分别为78.72%和87.23%，对照组分别为9.75%和0，两组比较差异有统计学意义（P<0.01）。观察组DD、cTnI单独检测时，其敏感度分别为78.72%、87.23%，特异度分别为90.24%、100%；而两项联合检测时，其敏感度增加至93.61%，特异度仍达95.12%。结论联合检测血浆DD与cTnI可明显提高AMI的早期诊断率。
目的探討D-二聚體（DD）和心肌肌鈣蛋白I（cTnI）聯閤檢測在急性心肌梗死（AMI）早期診斷中的臨床價值。方法對47例AMI患者（觀察組）及41例非心血管疾病患者（對照組）採血進行DD及cTnI定性測定併比較。結果觀察組DD及cTnI檢測暘性率分彆為78.72%和87.23%，對照組分彆為9.75%和0，兩組比較差異有統計學意義（P<0.01）。觀察組DD、cTnI單獨檢測時，其敏感度分彆為78.72%、87.23%，特異度分彆為90.24%、100%；而兩項聯閤檢測時，其敏感度增加至93.61%，特異度仍達95.12%。結論聯閤檢測血漿DD與cTnI可明顯提高AMI的早期診斷率。
목적탐토D-이취체（DD）화심기기개단백I（cTnI）연합검측재급성심기경사（AMI）조기진단중적림상개치。방법대47례AMI환자（관찰조）급41례비심혈관질병환자（대조조）채혈진행DD급cTnI정성측정병비교。결과관찰조DD급cTnI검측양성솔분별위78.72%화87.23%，대조조분별위9.75%화0，량조비교차이유통계학의의（P<0.01）。관찰조DD、cTnI단독검측시，기민감도분별위78.72%、87.23%，특이도분별위90.24%、100%；이량항연합검측시，기민감도증가지93.61%，특이도잉체95.12%。결론연합검측혈장DD여cTnI가명현제고AMI적조기진단솔。
Objective To investigate the clinical value of detecting D-Dimer(DD) combined with cTnI in the early diagnosis of acute myocardial infarction(AMI) . Methods The plasma DD and cTnI were determined and compared in 47 patients with AMI(observation group) and 41 patients excluding cardiovascular diseases (control group). Results The positive rates of DD and cTnI in observation group were higher than the control(78.72%vs 9.75%, 87.23%vs 0, both P<0.01). The separate test of DD and cTnI in observation group, sensitivity were 78.72%, 87.23%respectively, specificity were 90.24%, 100%respectively. While the union test, sensitivity and specificity were 93.61%, 95.12%. Conclusion Determining plasma DD combined with cTnI can obviously enhance the early diagnosis rate of AMI.
