中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
14期
447-448
,共2页
流感嗜血杆菌%耐药性%药敏试验%β- 内酰胺酶
流感嗜血桿菌%耐藥性%藥敏試驗%β- 內酰胺酶
류감기혈간균%내약성%약민시험%β- 내선알매
Haemophilus influenzae%Drug resistance%Drug sensitivity test%Beta-lactamases
目的了解东莞地区儿童呼吸道感染流感嗜血杆菌的季节分布及其耐药性情况。方法对东莞市妇幼保健院2011年1月至2012年12月5522例门诊和住院呼吸道感染患儿痰液标本，进行流感嗜血杆菌培养，分离、鉴定和药敏，利用 WHONET5.5软件进行分析。结果流感嗜血杆菌的阳性标本数为532株（9.63%），β-内酰胺酶产酶率为37.22%；春季（37.2%）为儿童感染高峰期，夏季（29.9%）次之，秋（13.2%）冬（19.7%）最少；氧氟沙星、头孢噻肟、利福平的敏感率达到98.1%、98.7%、98.9%，而复方新诺明的耐药率为75.2%，氨苄西林的耐药率为45.1%。结论东莞地区儿童呼吸道感染流感嗜血杆菌较为多见，与季节有关，其β-内酰胺酶产酶率较高，多数抗生素对流感嗜血杆菌的敏感性高，而氨苄西林、复方新诺明的耐药率高，不适于流感嗜血杆菌的治疗。
目的瞭解東莞地區兒童呼吸道感染流感嗜血桿菌的季節分佈及其耐藥性情況。方法對東莞市婦幼保健院2011年1月至2012年12月5522例門診和住院呼吸道感染患兒痰液標本，進行流感嗜血桿菌培養，分離、鑒定和藥敏，利用 WHONET5.5軟件進行分析。結果流感嗜血桿菌的暘性標本數為532株（9.63%），β-內酰胺酶產酶率為37.22%；春季（37.2%）為兒童感染高峰期，夏季（29.9%）次之，鞦（13.2%）鼕（19.7%）最少；氧氟沙星、頭孢噻肟、利福平的敏感率達到98.1%、98.7%、98.9%，而複方新諾明的耐藥率為75.2%，氨芐西林的耐藥率為45.1%。結論東莞地區兒童呼吸道感染流感嗜血桿菌較為多見，與季節有關，其β-內酰胺酶產酶率較高，多數抗生素對流感嗜血桿菌的敏感性高，而氨芐西林、複方新諾明的耐藥率高，不適于流感嗜血桿菌的治療。
목적료해동완지구인동호흡도감염류감기혈간균적계절분포급기내약성정황。방법대동완시부유보건원2011년1월지2012년12월5522례문진화주원호흡도감염환인담액표본，진행류감기혈간균배양，분리、감정화약민，이용 WHONET5.5연건진행분석。결과류감기혈간균적양성표본수위532주（9.63%），β-내선알매산매솔위37.22%；춘계（37.2%）위인동감염고봉기，하계（29.9%）차지，추（13.2%）동（19.7%）최소；양불사성、두포새우、리복평적민감솔체도98.1%、98.7%、98.9%，이복방신낙명적내약솔위75.2%，안변서림적내약솔위45.1%。결론동완지구인동호흡도감염류감기혈간균교위다견，여계절유관，기β-내선알매산매솔교고，다수항생소대류감기혈간균적민감성고，이안변서림、복방신낙명적내약솔고，불괄우류감기혈간균적치료。
Objective To investigate the distribution and drug resistance situation of season of Haemophilus influenzae in children with respiratory tract infections in Dongguan area. Methods The maternal and child health hospital in Dongguan city in 2011 January to 2012 December 5522 cases of outpatients and inpatients sputum specimens of respiratory tract infection, Haemophilus influenzae culture, isolation, identification and drug sensitivity, were analyzed using WHONET5.5 software. Results The number of positive specimens of Hemophilus influenza for 532 strains (9.63%), β-lactamase enzyme production rate was 37.22%; the spring (37.2%) at the peak of infection for children, summer (29.9%) times, autumn and winter (13.2%), (19.7%) at least; the sensitive rate of cefotaxime, ofloxacin, Rifuku Hira reached 98.1%, 98.7%, 98.9%, and compound sulfamethoxazole resistance rates were 75.2%, ampicillin resistant rate was 45.1%. Conclusion More common Haemophilus influenzae in children with respiratory tract infection in Dongguan area, with the seasons, the beta-lactamase enzyme production rate is high, the majority of antibiotic susceptibility of Haemophilus influenzae, and ampicillin, cotrimoxazole rate high, the treatment is not suitable for Haemophilus influenzae.
