CAJ | 학술논문

目的研究低浓度医用臭氧用于治疗膝骨性关节炎的临床效果。方法48例膝骨性关节炎患者随机分成两组，A 组为医用臭氧组，B组为注射生理盐水组。记录两组患者用药前（T0），用药后1周（T1）、1个月（T2）、3个月（T3）、6个月（T4）VAS 评分、WOMAC 关节炎指数评分。结果和治疗前比较，治疗后 A 组 VAS 评分、WOMAC 关节炎指数均显著性下降（P ＜0.01），而 B 组无显著性差异（P ＞0.05）；和 B 组比较，低浓度臭氧组（A 组）治疗后各时间点 VAS 评分显著性降低（P ＜0.05），WOMAC 关节炎指数显著性降低（P ＜0.01）。结论膝关节内注射低浓度臭氧能显著降低膝骨性关节炎患者的疼痛评分，改善患者 WOMAC 关节炎指数评分，是一种安全有效地治疗方法。
목적연구저농도의용취양용우치료슬골성관절염적림상효과。방법48례슬골성관절염환자수궤분성량조，A 조위의용취양조，B조위주사생리염수조。기록량조환자용약전（T0），용약후1주（T1）、1개월（T2）、3개월（T3）、6개월（T4）VAS 평분、WOMAC 관절염지수평분。결과화치료전비교，치료후 A 조 VAS 평분、WOMAC 관절염지수균현저성하강（P ＜0.01），이 B 조무현저성차이（P ＞0.05）；화 B 조비교，저농도취양조（A 조）치료후각시간점 VAS 평분현저성강저（P ＜0.05），WOMAC 관절염지수현저성강저（P ＜0.01）。결론슬관절내주사저농도취양능현저강저슬골성관절염환자적동통평분，개선환자 WOMAC 관절염지수평분，시일충안전유효지치료방법。
Objective To study the clinical effect low concentration of medical ozone for the treatment of knee osteoarthritis. Methods 48 cases of knee osteoarthritis were randomLy divided into two groups. A group is medical ozone group, B group is saline injection group. Record the two groups before treatment (T0), after administration of 1 week (T1), 1 month (T2), 3 (T3), 6 months (T4), VAS score, WOMAC arthritis index score. Results After treatment, the VAS score, the WOMAC arthritis index was significantly decreased (P <0.01) in two group. Compared with B group, the VAS and the WOMAC arthritis index score in A group after treatment at each time point significantly decreased (P <0.01). Conclusion Knee joint injection of low concentrations of ozone can significantly reduce pain scores of patients with knee osteoarthritis, Improve patients' WOMAC arthritis index scores, and is a safe and effective treatment.