CAJ | 학술논문

目的探讨孟鲁司特钠治疗儿童咳嗽变异性哮喘的临床治疗效果。方法回顾性分析，将2011年3月至2012年3月住我科的共90例咳嗽变异性哮喘患儿，随机分为两组，即观察组45例和对照组45例，对照组采用的治疗方法为口服盐酸丙卡特罗片和氯雷他定片，观察组的治疗方法是在对照组基础上口服孟鲁司特钠，应用治疗为3个月，比较两组的临床治疗效果。结果将两组的总有效率进行统计学比较，P ＜0.05，表明两组差异具有统计学意义，即观察组的总有效率显著高于对照组的总有效率。结论孟鲁司特钠在治疗儿童咳嗽变异性哮喘方面，具有疗效显著，不良反应少，依从性好等特点，值得临床推广使用。
목적탐토맹로사특납치료인동해수변이성효천적림상치료효과。방법회고성분석，장2011년3월지2012년3월주아과적공90례해수변이성효천환인，수궤분위량조，즉관찰조45례화대조조45례，대조조채용적치료방법위구복염산병잡특라편화록뢰타정편，관찰조적치료방법시재대조조기출상구복맹로사특납，응용치료위3개월，비교량조적림상치료효과。결과장량조적총유효솔진행통계학비교，P ＜0.05，표명량조차이구유통계학의의，즉관찰조적총유효솔현저고우대조조적총유효솔。결론맹로사특납재치료인동해수변이성효천방면，구유료효현저，불량반응소，의종성호등특점，치득림상추엄사용。
Objective To study the clinical effect of montelukast sodium tablets in the treatment of children with cough variant asthma. Methods A retrospective analysis in our outpatient clinic during March 2010 to March 2012, a total of 90 cases of children with cough variant asthma, who were randomly divided into two groups. An observation group of 45 patients and a control group of 45 patients. The treatment for the control group was using ambroxol hydrochloride and clenbuterol hydrochloride oral solution and loratadine dispersible tablets, and the treatment for children observed in the control group was using montelukast sodium chewable tablets on the basis of the treatment of the other group. Both treatments lasted for three months, and then we compared the clinical effect of the two groups. Results Total efficiency of the two groups were statistically compared, P<0.05, showing there was statistically significant difference between two groups. The total efficiency for the observation group was significantly higher than the total efficiency for the control group. Conclusion Montelukast sodium tablets have a significant effect in the treatment of children with cough variant asthma, with fewer adverse reactions, good compliance and it is worth for clinical use.