CAJ | 학술논문

目的探讨胃肠道间质瘤（GIST）的治疗方式及预后。方法回顾性分析2003年1月至2012年12月手术后经病理证实的43例GIST 病例资料。结果肿瘤发生于胃部25例，十二指肠1例，小肠12例，结肠4例，直肠1例。行腹腔镜下胃肿瘤切除术5例、直肠肿瘤切除1例；37例行开腹手术，29例完整切除，其中6例发现肝脏、大网膜转移，行联合脏器切除，2例广泛转移行姑息性手术。无手术死亡病例。30例获随访，9例术后复发，其中7例出现肝脏转移。结论手术切除是 GIST 治疗的首选，术前转移、Fletcher 分级和是否口服甲磺酸伊马替尼与疾病的预后密切相关
목적탐토위장도간질류（GIST）적치료방식급예후。방법회고성분석2003년1월지2012년12월수술후경병리증실적43례GIST 병례자료。결과종류발생우위부25례，십이지장1례，소장12례，결장4례，직장1례。행복강경하위종류절제술5례、직장종류절제1례；37례행개복수술，29례완정절제，기중6례발현간장、대망막전이，행연합장기절제，2례엄범전이행고식성수술。무수술사망병례。30례획수방，9례술후복발，기중7례출현간장전이。결론수술절제시 GIST 치료적수선，술전전이、Fletcher 분급화시부구복갑광산이마체니여질병적예후밀절상관
Objective Explore the treatment and prognosis of gastrointestinal stromal tumors (GIST). Methods The clinical data of 43 cases of GIST proved pathologically admitted from January 2003 to December 2012 at our hospital, were analyzed retrospectively. Results The tumors originated respectively from the, stomach(n=25), duodenum (n=1), intestine(n=12), colon (n=4), rectum(n=1) 5 cases of gastric and 1 cases of rectal GIST were performed by laparoscopic resection. 37 cases of GIST were performed by laparotomy. 29 cases were resected completely. six cases of liver, omental transfer take combined organ resection, 2 cases of extensive metastasis underwent palliative resection. There was no operative mortality. 30 cases were followed-up. 9 cases had recurrenced and metastisis, and7 of them were liver metastisis. Conclusion Resection is the first choice for treatment of GIST. Preoperative transfer fletcher classification and whether oral mesylate imatinib Nepal and the prognosis of the disease were closely related.