中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
15期
63-64
,共2页
免疫性血小板减少性紫癜%幽门螺旋杆菌%免疫功能
免疫性血小闆減少性紫癜%幽門螺鏇桿菌%免疫功能
면역성혈소판감소성자전%유문라선간균%면역공능
ITP%Helicobacter pylori%Immune function
目的分析免疫性血小板减少性紫癜合并幽门螺旋杆菌感染的患儿淋巴细胞免疫功能的变化。方法健康体检组为对照组。免疫性血小板减少性紫癜组为观察组及合并HP感染的ITP组为治疗组。在常规激素治疗基础上给予三联抗HP治疗。流式细胞仪检测患儿合并HP感染的CD4+，CD19+等抗体表达。结果 ITP组及合并HP感染的ITP组CD4+下降，CD4+/CD8+下降，CD19+升高与对照组相比有统计学意义，观察组与治疗组比较，HP感染的ITP组在CD4+/CD8+比值下降及CD19+增高较之ITP组更为明显，两组比较有统计学意义。结论 ITP患儿合并HP感染大多存在细胞及体液免疫功能异常。
目的分析免疫性血小闆減少性紫癜閤併幽門螺鏇桿菌感染的患兒淋巴細胞免疫功能的變化。方法健康體檢組為對照組。免疫性血小闆減少性紫癜組為觀察組及閤併HP感染的ITP組為治療組。在常規激素治療基礎上給予三聯抗HP治療。流式細胞儀檢測患兒閤併HP感染的CD4+，CD19+等抗體錶達。結果 ITP組及閤併HP感染的ITP組CD4+下降，CD4+/CD8+下降，CD19+升高與對照組相比有統計學意義，觀察組與治療組比較，HP感染的ITP組在CD4+/CD8+比值下降及CD19+增高較之ITP組更為明顯，兩組比較有統計學意義。結論 ITP患兒閤併HP感染大多存在細胞及體液免疫功能異常。
목적분석면역성혈소판감소성자전합병유문라선간균감염적환인림파세포면역공능적변화。방법건강체검조위대조조。면역성혈소판감소성자전조위관찰조급합병HP감염적ITP조위치료조。재상규격소치료기출상급여삼련항HP치료。류식세포의검측환인합병HP감염적CD4+，CD19+등항체표체。결과 ITP조급합병HP감염적ITP조CD4+하강，CD4+/CD8+하강，CD19+승고여대조조상비유통계학의의，관찰조여치료조비교，HP감염적ITP조재CD4+/CD8+비치하강급CD19+증고교지ITP조경위명현，량조비교유통계학의의。결론 ITP환인합병HP감염대다존재세포급체액면역공능이상。
Objective?To examine immune function of lymphocyte sub-type cells of children with acute ITP of Helicobacter pylori(HP) infection. Methods control group is health examination children.ITP group and ITP with HP fectionn are observe group. On hormone therapy treatment, resisting HP treatment was given to ITP with HP. To examine antibodys such as CD4, CD19 to group ITP with HP, adopting double cloning antibody immunofluorescence and with stream cell machine. Results In both groups of ITP and ITP with HP,there were a significant decrease in CD4+, CD4+/CD8+and a significant increase in CD19+,with P<0.01;the change of CD4+/CD8+and CD19+of ITP with HP were significantly more than those of ITP, with P<0.01. Conclusions ITP with Hp infection has significantly disfunction on cellular immune function and humoral immune function.
