白求恩医学杂志
白求恩醫學雜誌
백구은의학잡지
Journal of Bethune Military Medical College
2014年
4期
330-331
,共2页
肺表面活性物质%鼻塞式气道正压通气%新生儿呼吸窘迫综合征
肺錶麵活性物質%鼻塞式氣道正壓通氣%新生兒呼吸窘迫綜閤徵
폐표면활성물질%비새식기도정압통기%신생인호흡군박종합정
Pulmonary surfactant%Nasal continuous positive airway pressure%Neonatal respiratory distress syndrome
目的:探讨肺表面活性物质(PS)联合鼻塞式气道正压通气(NCPAP)治疗新生儿呼吸窘迫综合征(NRDS)的临床效果。方法将72例NRDS患儿随机分为两组,各36例。两组均给予常规对症治疗,观察组在此基础上给予PS+NCPAP治疗,对照组在此基础上给予PS+机械通气( MV)治疗,比较两组治疗效果、并发症发生率、氧疗时间及住院时间。结果观察组治疗总有效率为94.44%,高于对照组的77.78%( P <0.05);观察组并发症发生率为13.89%(5/36),对照组并发症发生率为36.11%(13/36),观察组并发症发生率低于对照组( P <0.05);观察组氧疗时间和住院时间均短于对照组( P <0.01)。结论 PS联合NCPAP治疗NRDS能有效减少氧疗时间、降低并发症发生率及缩短住院时间。
目的:探討肺錶麵活性物質(PS)聯閤鼻塞式氣道正壓通氣(NCPAP)治療新生兒呼吸窘迫綜閤徵(NRDS)的臨床效果。方法將72例NRDS患兒隨機分為兩組,各36例。兩組均給予常規對癥治療,觀察組在此基礎上給予PS+NCPAP治療,對照組在此基礎上給予PS+機械通氣( MV)治療,比較兩組治療效果、併髮癥髮生率、氧療時間及住院時間。結果觀察組治療總有效率為94.44%,高于對照組的77.78%( P <0.05);觀察組併髮癥髮生率為13.89%(5/36),對照組併髮癥髮生率為36.11%(13/36),觀察組併髮癥髮生率低于對照組( P <0.05);觀察組氧療時間和住院時間均短于對照組( P <0.01)。結論 PS聯閤NCPAP治療NRDS能有效減少氧療時間、降低併髮癥髮生率及縮短住院時間。
목적:탐토폐표면활성물질(PS)연합비새식기도정압통기(NCPAP)치료신생인호흡군박종합정(NRDS)적림상효과。방법장72례NRDS환인수궤분위량조,각36례。량조균급여상규대증치료,관찰조재차기출상급여PS+NCPAP치료,대조조재차기출상급여PS+궤계통기( MV)치료,비교량조치료효과、병발증발생솔、양료시간급주원시간。결과관찰조치료총유효솔위94.44%,고우대조조적77.78%( P <0.05);관찰조병발증발생솔위13.89%(5/36),대조조병발증발생솔위36.11%(13/36),관찰조병발증발생솔저우대조조( P <0.05);관찰조양료시간화주원시간균단우대조조( P <0.01)。결론 PS연합NCPAP치료NRDS능유효감소양료시간、강저병발증발생솔급축단주원시간。
Objective To study effect of pulmonary surfactant and NCPAP on neonatal respiratory distress syndrome ( NRDS) . Methods Seventy-two children with NRDS were divided into observation group and control group ( n =36,each),and observation group was given PS +NCPAP,control group was given PS +mechanical ventilation (MV),treatment effects,oxygen treatment time, length of hospital stay,complications were compared .Results The total efficacy rate of observation group was 94.44%,higher than 77.78%of control group( P <0.05).The complication rate was 13.89%(5/36),lower than 36.11%(13/36)of control group( P <0.05).Oxygen treatment time and complication rate were lower than that of control group ( P <0.01).Conclusion Pulmonary surfac-tant and NCPAP can effectively reduce oxygen treatment time , the incidence rate of complications and length of hospital stay .