检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2014年
12期
1634-1635
,共2页
高血压%门静脉%腹腔积液%食管和胃静脉曲张
高血壓%門靜脈%腹腔積液%食管和胃靜脈麯張
고혈압%문정맥%복강적액%식관화위정맥곡장
hypertension%portal vein%ascites%esophageal and gastric varices
目的:探讨血清腹水清蛋白梯度(SAAG)与门静脉高压症食管胃底静脉破裂出血的关系。方法对2009~2011年冀中能源峰峰集团总医院门静脉高压症并发食管胃底静脉曲张破裂患者36例行选择性断流手术(观察组),另选取同期40例食管胃底静脉曲张未出血患者作为对照组,2组患者的年龄、门静脉宽度、总胆红素、SAAG、部分凝血活酶时间(APTT)值进行比较,同时对出血手术患者SAAG和门静脉压力梯度(PPG)变化值行直线相关性分析。通过受试者工作特征(ROC)曲线确定血清SAAG对门静脉高压症食管胃底静脉破裂出血的预测值。结果观察组患者SAAG为(24.2±7.1) g/L ,对照组患者SAAG为(15.2±6.0) g/L ,2组比较差异有统计学意义(P<0.05)。观察组患者SAAG与PPG变化值两者之间存在正相关(r=0.84,P<0.01),利用ROC曲线确定SAAG并预测门静脉高压症食管胃底静脉破裂出血的最佳诊断切点为18.3 g/L ,敏感度和特异度分别为95.1%和66.1%。结论血清SAAG是预测门静脉高压症食管胃底静脉破裂出血的良好指标。
目的:探討血清腹水清蛋白梯度(SAAG)與門靜脈高壓癥食管胃底靜脈破裂齣血的關繫。方法對2009~2011年冀中能源峰峰集糰總醫院門靜脈高壓癥併髮食管胃底靜脈麯張破裂患者36例行選擇性斷流手術(觀察組),另選取同期40例食管胃底靜脈麯張未齣血患者作為對照組,2組患者的年齡、門靜脈寬度、總膽紅素、SAAG、部分凝血活酶時間(APTT)值進行比較,同時對齣血手術患者SAAG和門靜脈壓力梯度(PPG)變化值行直線相關性分析。通過受試者工作特徵(ROC)麯線確定血清SAAG對門靜脈高壓癥食管胃底靜脈破裂齣血的預測值。結果觀察組患者SAAG為(24.2±7.1) g/L ,對照組患者SAAG為(15.2±6.0) g/L ,2組比較差異有統計學意義(P<0.05)。觀察組患者SAAG與PPG變化值兩者之間存在正相關(r=0.84,P<0.01),利用ROC麯線確定SAAG併預測門靜脈高壓癥食管胃底靜脈破裂齣血的最佳診斷切點為18.3 g/L ,敏感度和特異度分彆為95.1%和66.1%。結論血清SAAG是預測門靜脈高壓癥食管胃底靜脈破裂齣血的良好指標。
목적:탐토혈청복수청단백제도(SAAG)여문정맥고압증식관위저정맥파렬출혈적관계。방법대2009~2011년기중능원봉봉집단총의원문정맥고압증병발식관위저정맥곡장파렬환자36례행선택성단류수술(관찰조),령선취동기40례식관위저정맥곡장미출혈환자작위대조조,2조환자적년령、문정맥관도、총담홍소、SAAG、부분응혈활매시간(APTT)치진행비교,동시대출혈수술환자SAAG화문정맥압력제도(PPG)변화치행직선상관성분석。통과수시자공작특정(ROC)곡선학정혈청SAAG대문정맥고압증식관위저정맥파렬출혈적예측치。결과관찰조환자SAAG위(24.2±7.1) g/L ,대조조환자SAAG위(15.2±6.0) g/L ,2조비교차이유통계학의의(P<0.05)。관찰조환자SAAG여PPG변화치량자지간존재정상관(r=0.84,P<0.01),이용ROC곡선학정SAAG병예측문정맥고압증식관위저정맥파렬출혈적최가진단절점위18.3 g/L ,민감도화특이도분별위95.1%화66.1%。결론혈청SAAG시예측문정맥고압증식관위저정맥파렬출혈적량호지표。
Objective To investigate the relationship between the serum-ascites albumin gradient(SAAG) and portal hypertension esophageal and gastric fundus variceal bleeding .Methods A cases of 36 esophageal gastric fun-dus variceal bleeding of portal hypertension under going selective devascularization and splenectomy were enrolled from 2009 to 2011 at General Hospital of Fengfeng Jizhong energy group ,at the same time ,40 cases of esophageal and gastric varices without hemorrhage were selected as control group .Age ,portal vein width ,total bilirubin ,SAAG , activated partial thromboplastin time(APTT) were contrasted between two groups .measured preoperative and post-operative SAAG and portal vein pressure gradient (PPG) .The correlation between PPG and SAAG was explored . The value of SAAG predicting esophageal-gastric fundus varices rupture was confirmed by receiver operating charac-teristic curve(ROC) .Results SAAG of bleeding patients was (24 .2 ± 7 .1)g/L ,SAAG of non bleeding was (15 .2 ± 6 .0)g/L .The difference of SAAG and APTT in two groups was significant .The changes of SAAG were positive cor-relation with PPG changes (r=0 .84 ,P<0 .01) .Using receiver operating characteristic curves (ROC) ,the SAAG val-ue predicting esophageal and gastric variceal bleeding was 18 .30 g/L ,sensitivity and specificity were 95 .1% and 66 .1% .Conclusion serum-ascites albumin gradient is a good indicator predicting esophageal and gastric variceal bleeding .