CAJ | 학술논문

目的：分析ALT初筛后献血ALT不合格率较高的原因。方法随机抽取ALT未筛查组（对照组）及筛查组献血者各10647人次与12129人次，分别统计ALT、HBsAg、抗HCV、抗HIV、抗TP 不合格情况，对筛查组ALT不合格标本进行外观检查并用干式生化进行复查，观察街头筛查与实验室检测结果的一致性。结果筛查组比对照组ALT、抗HCV阳性率及总不合格率下降明显，而HBsAg、抗TP阳性率下降不明显；筛查组ALT不合格标本以乳糜血等异常情况占多数；街头干式生化筛查ALT有一定的漏检。结论献血前筛查还需增加乳糜血筛查，同时，加强街头筛查质量控制，才能进一步提高血液合格率。
목적：분석ALT초사후헌혈ALT불합격솔교고적원인。방법수궤추취ALT미사사조（대조조）급사사조헌혈자각10647인차여12129인차，분별통계ALT、HBsAg、항HCV、항HIV、항TP 불합격정황，대사사조ALT불합격표본진행외관검사병용간식생화진행복사，관찰가두사사여실험실검측결과적일치성。결과사사조비대조조ALT、항HCV양성솔급총불합격솔하강명현，이HBsAg、항TP양성솔하강불명현；사사조ALT불합격표본이유미혈등이상정황점다수；가두간식생화사사ALT유일정적루검。결론헌혈전사사환수증가유미혈사사，동시，가강가두사사질량공제，재능진일보제고혈액합격솔。
Objective To analyze the reason why ALT had high failure rate after blood donor screening. Methods Ran-domly selected 10647 blood donors as control group and 12129 blood donors as the screening group, statistics for the failure rate of ALT, HBsAg, anti-HCV, anti-HIV and anti-TP. In the screening group, visually inspect ALT unquali-fied specimens and review on dry type biochemistry analyzer. Analyzed the consistencies between the street screening results and laboratory test results. Results The ALT, anti HCV positive rate and total unqualified rate of screening group decreased more significantly than that of the control group, but the HBsAg, anti TP positive rate decreased in-conspicuously. Most of the reasons for ALT unqualified in the screening group was chyle blood abnormalities. Screening for ALT on street dry type biochemistry analyzer had some missing. Conclusion In order to improve the qualified rate of blood, chyle blood screening is necessary before blood donor screening, moreover, we should strengthen the quality control of street screening.