中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2013年
11期
1159-1160
,共2页
冠心病%心律失常,心性%美托洛尔
冠心病%心律失常,心性%美託洛爾
관심병%심률실상,심성%미탁락이
Coronary disease%Arrhythmia,cardiac%Metoprolol
目的 探讨稳心颗粒联合美托洛尔治疗老年人冠心病心律失常的疗效及其安全性.方法 回顾性分析186例老年人冠心病心律失常临床资料,根据药物治疗方案分为稳心颗粒组62例;美托洛尔组60例;联合组64例采用稳心颗粒联合美托洛尔治疗.观察入选患者临床治疗效果及其不良反应. 结果 联合组显效率和总有效率[53.1％(34例)、93.8％(60例)]高于稳心颗粒组[32.3％(20例)、40.3％(25例)]、美托洛尔组[30.0％(18例)、40.0％(24例),x2值分别为10.736、11.342,均P＜0.05].联合组显效率和总有效率较稳心颗粒组和美托洛尔组高(均P＜0.05).3组不良反应发生率分别为4.8％(3/62)、8.3％(5/60)和8.3％(5/64),均P＞0.05. 结论 稳心颗粒和美托洛尔的联合应用治疗老年冠心病心律失常,减少期前收缩次数,安全性好.
目的 探討穩心顆粒聯閤美託洛爾治療老年人冠心病心律失常的療效及其安全性.方法 迴顧性分析186例老年人冠心病心律失常臨床資料,根據藥物治療方案分為穩心顆粒組62例;美託洛爾組60例;聯閤組64例採用穩心顆粒聯閤美託洛爾治療.觀察入選患者臨床治療效果及其不良反應. 結果 聯閤組顯效率和總有效率[53.1％(34例)、93.8％(60例)]高于穩心顆粒組[32.3％(20例)、40.3％(25例)]、美託洛爾組[30.0％(18例)、40.0％(24例),x2值分彆為10.736、11.342,均P＜0.05].聯閤組顯效率和總有效率較穩心顆粒組和美託洛爾組高(均P＜0.05).3組不良反應髮生率分彆為4.8％(3/62)、8.3％(5/60)和8.3％(5/64),均P＞0.05. 結論 穩心顆粒和美託洛爾的聯閤應用治療老年冠心病心律失常,減少期前收縮次數,安全性好.
목적 탐토은심과립연합미탁락이치료노년인관심병심률실상적료효급기안전성.방법 회고성분석186례노년인관심병심률실상림상자료,근거약물치료방안분위은심과립조62례;미탁락이조60례;연합조64례채용은심과립연합미탁락이치료.관찰입선환자림상치료효과급기불량반응. 결과 연합조현효솔화총유효솔[53.1％(34례)、93.8％(60례)]고우은심과립조[32.3％(20례)、40.3％(25례)]、미탁락이조[30.0％(18례)、40.0％(24례),x2치분별위10.736、11.342,균P＜0.05].연합조현효솔화총유효솔교은심과립조화미탁락이조고(균P＜0.05).3조불량반응발생솔분별위4.8％(3/62)、8.3％(5/60)화8.3％(5/64),균P＞0.05. 결론 은심과립화미탁락이적연합응용치료노년관심병심률실상,감소기전수축차수,안전성호.
Objective To explore the clinical effect and safety of Wenxin granule combined with metoprolol on arrhythmia in elderly patients with coronary heart disease (CHD).Methods 186 elderly CHD patients with arrhythmia were divided into 3 groups according to therapy:group A (n=62,treated with Wenxin granule),group B (n=60,treated with metoprolol) and group C (n=64,treated with Wenxin granule plus metoprolol).Clinical effect and adverse effect were retrospectively analyzed.Results The excellence rate and total efficiency rate were higher in group C than group A andB [53.1％ (34 cases) vs.32.3％ (20 cases),30.0％ (18 cases); 93.8％ (60 cases) vs.40.3％ (25 cases),40.0％ (24 cases) ; respectively,all P＜0.05].There were no significant differences in the incidence of adverse effect in the 3 groups [4.8％ (3/62),8.3％ (5/60) vs.8.3％ (5/64),all P ＞0.05].Conclusions Wenxin granule combined with metoprolol improves clinical effect,decreases premature beat and has a better safety for elderly CHD patients with arrhythmia,which is worthy of clinical application.
