CAJ | 학술논문

目的根据36 809例健康体检人群空腹血糖水平(FPG)及血糖异常年龄分布特征,探讨健康体检人群的糖代谢功能.方法对2008年7月至2013年7月在广东省第二人民医院体检中心参加健康体检的36 809名体检者的FPG检测结果进行统计分析,按照年龄分为7组并比较分析空腹血糖与性别、年龄的关系.结果随着年龄的增长,FPG呈现逐渐增高的趋势,两者呈正相关(r=0.266,P＜ 0.001);各年龄段的男性FPG均高于女性FPG,20～69岁各年龄阶段男女比较差异有统计学意义(P＜0.01).FPG升高的检出率也随着年龄的增长而增高,且各年龄段的男性检出率高于女性,在20～59岁各年龄阶段男女比较差异具有统计学意义(P＜0.01).降低IFG切点可显著增加高血糖人员的检出率.当FPG≥7.0 mmol/L时,男性血糖平均水平、人数构成比均高于女性(P=0.019,0.000).结论该体检人群的FPG水平以及血糖增高检出率均随年龄的增长而增加,并且血糖增高的检出呈现年轻化趋势,因此,我们应当对各年龄组人群都给予足够的监测与预防指导;体检空腹血糖是发现血糖增高的重要途径,降低IFG切点有助于提高预测糖尿病发生的敏感性.
목적 근거36 809례건강체검인군공복혈당수평(FPG)급혈당이상년령분포특정,탐토건강체검인군적당대사공능.방법 대2008년7월지2013년7월재광동성제이인민의원체검중심삼가건강체검적36 809명체검자적FPG검측결과진행통계분석,안조년령분위7조병비교분석공복혈당여성별、년령적관계.결과 수착년령적증장,FPG정현축점증고적추세,량자정정상관(r=0.266,P＜ 0.001);각년령단적남성FPG균고우녀성FPG,20～69세각년령계단남녀비교차이유통계학의의(P＜0.01).FPG승고적검출솔야수착년령적증장이증고,차각년령단적남성검출솔고우녀성,재20～59세각년령계단남녀비교차이구유통계학의의(P＜0.01).강저IFG절점가현저증가고혈당인원적검출솔.당FPG≥7.0 mmol/L시,남성혈당평균수평、인수구성비균고우녀성(P=0.019,0.000).결론 해체검인군적FPG수평이급혈당증고검출솔균수년령적증장이증가,병차혈당증고적검출정현년경화추세,인차,아문응당대각년령조인군도급여족구적감측여예방지도;체검공복혈당시발현혈당증고적중요도경,강저IFG절점유조우제고예측당뇨병발생적민감성.
Objective To explore the sugar metabolism of 36,809 individuals receiving physical examination basing on their blood sugar levels and the age distribution characteristics of abnormal blood sugar.Methods The clinical data of 36,809 individuals receiving physical examination at Second People's Hospital of Guangdong Province from July,2008 to July,2013 were statistically analyzed.They were divided into 7 groups according to their ages.The FPG records and its relationship with sex and age were compared and analyzed.Results FPG gradually increased with and positively correlated with age (r =0.266,P ＜ 0.001).The FPG level was higher in the male than in the female in all age groups,with statistical differences between the groups 20 to 69 years old (P ＜ 0.01).The hyperglycemia' s detection rate increased with age and was higher in the male than in the female,with statistical differences between the groups 20 to 59 years old (P ＜ 0.01).The detection rate would be increased if the cut-off point of IFG was reduced.The average blood glucose levels and the number constituent ratio of the male were higher than those of the female when the FPG was over 7.0 mmol/L (P=0.019,0.000).Conclusions These people' s fasting plasma glucose levels and hyperglycemia detection rate increased with age; the detection of hyperglycemia was getting younger and younger.Therefore,sufficient guidance for monitoring and prevention is needed.Examining fasting blood glucose is an important way for discovering hyperglycemia.Lowering the IFG cut-point helps improve the prediction of diabetes susceptibility.