中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2013年
19期
32-33
,共2页
地佐辛%芬太尼%丙泊酚%无痛胃镜
地佐辛%芬太尼%丙泊酚%無痛胃鏡
지좌신%분태니%병박분%무통위경
Dezocine%Fentany%Propofol%Painless endoscopy
目的:研究对比地佐辛和芬太尼用于老年人无痛胃镜检查的麻醉效果和临床安全性。方法:将行无痛胃镜检查的老年患者100例随机分为地佐辛组(D 组,n=50)和芬太尼组(F 组,n=50),D 组患者静脉注射地佐辛0.05 mg/kg,F 组患者静脉注射芬太尼1μg/kg,之后两组患者分别间隔4 min 和1 min 开始静脉注射丙泊酚1~2 mg/kg,至患者睫毛反射消失后开始做胃镜检查。记录两组患者用药前,用药后2 min,苏醒时的 HR、MAP、SpO2,记录两组患者丙泊酚总用量、手术时间、唤醒时间、苏醒时镇静评分以及麻醉期间的不良反应等。结果:两组患者用药后2 min 的 HR、MAP、SpO2均较注药前下降明显(P<0.05),且 F 组患者用药后2 min 的 SpO2低于 D 组(P<0.05)。两组患者丙泊酚总用量、手术时间、唤醒时间组间比较差异无统计学意义(P>0.05),但 D 组患者苏醒时镇静评分低于 F 组,麻醉期间的不良反应少(P<0.05)。结论:0.05 mg/kg 地佐辛复合丙泊酚相比较1μg/kg 芬太尼复合丙泊酚更适用于老年人无痛胃镜检查,麻醉效果确切,呼吸抑制减少,苏醒时清醒程度高,且不良反应少。
目的:研究對比地佐辛和芬太尼用于老年人無痛胃鏡檢查的痳醉效果和臨床安全性。方法:將行無痛胃鏡檢查的老年患者100例隨機分為地佐辛組(D 組,n=50)和芬太尼組(F 組,n=50),D 組患者靜脈註射地佐辛0.05 mg/kg,F 組患者靜脈註射芬太尼1μg/kg,之後兩組患者分彆間隔4 min 和1 min 開始靜脈註射丙泊酚1~2 mg/kg,至患者睫毛反射消失後開始做胃鏡檢查。記錄兩組患者用藥前,用藥後2 min,囌醒時的 HR、MAP、SpO2,記錄兩組患者丙泊酚總用量、手術時間、喚醒時間、囌醒時鎮靜評分以及痳醉期間的不良反應等。結果:兩組患者用藥後2 min 的 HR、MAP、SpO2均較註藥前下降明顯(P<0.05),且 F 組患者用藥後2 min 的 SpO2低于 D 組(P<0.05)。兩組患者丙泊酚總用量、手術時間、喚醒時間組間比較差異無統計學意義(P>0.05),但 D 組患者囌醒時鎮靜評分低于 F 組,痳醉期間的不良反應少(P<0.05)。結論:0.05 mg/kg 地佐辛複閤丙泊酚相比較1μg/kg 芬太尼複閤丙泊酚更適用于老年人無痛胃鏡檢查,痳醉效果確切,呼吸抑製減少,囌醒時清醒程度高,且不良反應少。
목적:연구대비지좌신화분태니용우노년인무통위경검사적마취효과화림상안전성。방법:장행무통위경검사적노년환자100례수궤분위지좌신조(D 조,n=50)화분태니조(F 조,n=50),D 조환자정맥주사지좌신0.05 mg/kg,F 조환자정맥주사분태니1μg/kg,지후량조환자분별간격4 min 화1 min 개시정맥주사병박분1~2 mg/kg,지환자첩모반사소실후개시주위경검사。기록량조환자용약전,용약후2 min,소성시적 HR、MAP、SpO2,기록량조환자병박분총용량、수술시간、환성시간、소성시진정평분이급마취기간적불량반응등。결과:량조환자용약후2 min 적 HR、MAP、SpO2균교주약전하강명현(P<0.05),차 F 조환자용약후2 min 적 SpO2저우 D 조(P<0.05)。량조환자병박분총용량、수술시간、환성시간조간비교차이무통계학의의(P>0.05),단 D 조환자소성시진정평분저우 F 조,마취기간적불량반응소(P<0.05)。결론:0.05 mg/kg 지좌신복합병박분상비교1μg/kg 분태니복합병박분경괄용우노년인무통위경검사,마취효과학절,호흡억제감소,소성시청성정도고,차불량반응소。
Objective:To compare the clinical effects and safety of dezocine and fentany in elderly patients undergoing painless endoscopy. Method:One hundred elderly patients undergoing painless endoscopy were randomly divided into dezocine group(group D,n=50)and fentany group (group F,n=50).Group D was given dezocine 0.05 mg/kg and Group F was given fentany 1 μg/kg,then two group of patients,respectively,after the interval of 4 minutes and 1 minutes were given propofol 1-2 mg/kg,the endoscopy were performed after the eyelash reflex disappeared.Heart rate(HR), mean arterial pressure(MAP),saturation of peripheral oxygen(SpO2)were recorded before anesthesia,two minutes after anesthesia and awakening. Recorded the sum of propofol,operating time,awakening time,the ramsay and adverse reactions in two groups.Result:The levels of HR MAP and SpO2 of two groups during endoscopy were decreased(P<0.05),while the level of SpO2 of group F during endoscopy were lower than group D(P<0.05).the sum of propofol,operating time and awakening time showed no significant difference between two groups(P>0.05),but the Ramsay of group D was lower than group F,and there were fewer adverse reactions in group D(P<0.05).Conclusion:0.05 mg/kg dezocine is more suitable for the elderly patients than 1μg/kg fentany,it has exact effect of anesthesia,less respiratory depression,higher level of consciousness awakening and fewer adverse reactions.