世界科学技术-中医药现代化
世界科學技術-中醫藥現代化
세계과학기술-중의약현대화
WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE
2013年
3期
495-500
,共6页
刘珺瑶%辛宁%周福军%单淇%于冰%侯文彬
劉珺瑤%辛寧%週福軍%單淇%于冰%侯文彬
류군요%신저%주복군%단기%우빙%후문빈
溃疡性结肠炎%UC作用机制%UC动物模型
潰瘍性結腸炎%UC作用機製%UC動物模型
궤양성결장염%UC작용궤제%UC동물모형
Ulcerative colitis (UC)%UC mechanism%UC animal model
溃疡性结肠炎(UC)是一种直肠和结肠慢性非特异性疾病,病因尚不明确,常反复发作,治疗难度较大,严重影响患者日常的生活和工作。针对中医药治疗溃疡性结肠炎疾病现状及存在问题,结合本人对新药研发的体会,提出治疗UC的中药新药研究思路,包括建立符合中医药特色的作用机制及UC动物模型,选择合适的临床治疗点等。
潰瘍性結腸炎(UC)是一種直腸和結腸慢性非特異性疾病,病因尚不明確,常反複髮作,治療難度較大,嚴重影響患者日常的生活和工作。針對中醫藥治療潰瘍性結腸炎疾病現狀及存在問題,結閤本人對新藥研髮的體會,提齣治療UC的中藥新藥研究思路,包括建立符閤中醫藥特色的作用機製及UC動物模型,選擇閤適的臨床治療點等。
궤양성결장염(UC)시일충직장화결장만성비특이성질병,병인상불명학,상반복발작,치료난도교대,엄중영향환자일상적생활화공작。침대중의약치료궤양성결장염질병현상급존재문제,결합본인대신약연발적체회,제출치료UC적중약신약연구사로,포괄건립부합중의약특색적작용궤제급UC동물모형,선택합괄적림상치료점등。
Ulcerative colitis (UC) is a chronic non-specific disease of the rectum and colon. The disease cause is still unclear. Due to the repeated episodes of UC, the treatment is very difficult. There are serious impact on pa-tients' life and work. According to the current UC condition and existed problems with Chinese medicine treat-ment and in combination with experiences of new Chinese medicine drug development of the author, a new Chi-nese medicine drug research idea of UC has been proposed. It includes the establishment of UC animal model in line with the characteristics of Chinese medicine and the selection of appropriate clinical treatment targets.