他汀类药物中间体(S)-4-氯-3-羟基丁酸乙酯生物催化合成的研究进展
타정류약물중간체(S)-4-록-3-간기정산을지생물최화합성적연구진전
Research progress on biocatalysis of (S)-4-chloro-3-hydroxybutanoate esters used for the intermediates of statins drugs
  • 万方数据
    世界临床药物 세계림상약물
    WORLD CLINICAL DRUGS
    2013年 6期 359-363 ,共5页

    陶源%胡又佳%周斌%朱宝泉

    도원%호우가%주빈%주보천

    (S)-4-氯-3-羟基丁酸乙酯%他汀类药物%生物催化 (S)-4-氯-3-羥基丁痠乙酯%他汀類藥物%生物催化
    (S)-4-록-3-간기정산을지%타정류약물%생물최화
    ethyl (S)-4-chloro-3-hydroxybutanoate ester%statins%biocatalysis
    (S)-4-氯-3-羟基丁酸乙酯[(S)-CHBE]是羟甲戊二酰辅酶A还原酶抑制剂即他汀类药物的关键手性中间体.本文综述生物催化合成(S)-CHBE的研究进展.
    (S)-4-록-3-간기정산을지[(S)-CHBE]시간갑무이선보매A환원매억제제즉타정류약물적관건수성중간체.본문종술생물최화합성(S)-CHBE적연구진전.
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