CAJ | 학술논문

目的：探讨颈动脉粥样硬化与冠心病严重程度的相关性。方法应用颈动脉超声检查急性心肌梗死（AMI）患者、不稳定型心绞痛患者、经冠脉造影检查除外冠心病的患者（对照组）的颈动脉内中膜厚度（IMT）并计算其Crouse 积分，观察3组之间 IMT、Crouse 积分的差异和相关性；冠脉造影检查判断冠状动脉粥样硬化病变情况，再将以上患者分为非冠心病组、单支病变组、双支病变组和多支病变组，采用 Gensini 评分评判严重程度，观察各组之间Gensini 评分的差异，并将 IMT、Crouse 积分与 Gensini 评分行相关性分析，得出颈动脉粥样硬化与冠状动脉粥样硬化严重程度的相关性。结果AMI、UA 组与对照组 IMT 值及 Crouse 积分有显著性差异（P ＜0．05），非冠心病组、单支病变组、双支病变组和多支病变组 IMT 值及 Crouse 积分有显著性差异（P ＜0．05），Crouse 积分与 Gensini 评分具有相关性。结论颈动脉粥样硬化的严重程度可以作为冠心病严重程度的预测因子。
목적：탐토경동맥죽양경화여관심병엄중정도적상관성。방법응용경동맥초성검사급성심기경사（AMI）환자、불은정형심교통환자、경관맥조영검사제외관심병적환자（대조조）적경동맥내중막후도（IMT）병계산기Crouse 적분，관찰3조지간 IMT、Crouse 적분적차이화상관성；관맥조영검사판단관상동맥죽양경화병변정황，재장이상환자분위비관심병조、단지병변조、쌍지병변조화다지병변조，채용 Gensini 평분평판엄중정도，관찰각조지간Gensini 평분적차이，병장 IMT、Crouse 적분여 Gensini 평분행상관성분석，득출경동맥죽양경화여관상동맥죽양경화엄중정도적상관성。결과AMI、UA 조여대조조 IMT 치급 Crouse 적분유현저성차이（P ＜0．05），비관심병조、단지병변조、쌍지병변조화다지병변조 IMT 치급 Crouse 적분유현저성차이（P ＜0．05），Crouse 적분여 Gensini 평분구유상관성。결론경동맥죽양경화적엄중정도가이작위관심병엄중정도적예측인자。
Objective To investigate the correlation between Carotid Atherosclerotic with extent of coronary heart disease(CAD).Methods The IMT and Crouse score were measured in patients with acute myocardial infarction (AMI),patients with acute unstable angina (UA)and normol control group by carotid ultrasonography.Patients in CAD group were separated into 3 subgorups based on coronary artery pathological changes including single vessel,two vessel and multi-vessel coronary disease,and the severity of coronary artery was graded according to Gensini score sys-tem respectively.Results The IMT and Crouse score were significantly increased in both AMI group and UA group compared with those in control group(P<0.05).The IMT and Crouse score were significantly increased in AMI group com-pared with that in UA group(P<0.05).The IMT and Crouse score were significantly increased in single vessel,two vessel and multi-vessel coronary disease group than that in nan-coronary heart disease group.Conclusion IMT and Crouse score are in-creased in patients with CAD and their rises are the predictive factors of the severity of coronary heart disease.