CAJ | 학술논문

目的：探究氟桂利嗪联合舒马普坦治疗丛集性头痛急性期的效果。方法104例丛集性头痛患者分为实验组与对照组，实验组使用氟桂利嗪于舒马普坦联合治疗，对照组仅用舒马普坦治疗，比较2组治疗后丛集期长度减少时间、发作次数、头痛程度及总有效率等。结果2组治疗后较治疗前丛集期的长度、发作次数及头痛程度都明显降低，差异有统计学意义（P＜0.05）。实验组丛集期长度、发作次数以及头痛程度均明显低于对照组，差异有统计学意义，（P＜0.05）。实验组的总有效率98.08％，对照组为86.54％，实验组明显高于对照组（χ2＝6.407，P＝0.040）。结论氟桂利嗪联合舒马普坦治疗丛集性头痛急性期比单独使用舒马普坦效果更优。
목적：탐구불계리진연합서마보탄치료총집성두통급성기적효과。방법104례총집성두통환자분위실험조여대조조，실험조사용불계리진우서마보탄연합치료，대조조부용서마보탄치료，비교2조치료후총집기장도감소시간、발작차수、두통정도급총유효솔등。결과2조치료후교치료전총집기적장도、발작차수급두통정도도명현강저，차이유통계학의의（P＜0.05）。실험조총집기장도、발작차수이급두통정도균명현저우대조조，차이유통계학의의，（P＜0.05）。실험조적총유효솔98.08％，대조조위86.54％，실험조명현고우대조조（χ2＝6.407，P＝0.040）。결론불계리진연합서마보탄치료총집성두통급성기비단독사용서마보탄효과경우。
Objective To evaluate the effect of Flunarizine combined with Sumatriptan on acute cluster headache. Methods Totally 104 patients with acute cluster headache were selected ,and were divided into the experimental group and the control group ,the first group were treated with Flunarizine combined with Sumatriptan ,the last group were treated only by Sumatrip-tan. After the treatment ,the severity of headache and the total efficacy rate of two groups were compared.Results The severi-ty of headache of the two groups was lower than that of before treatment (P<0.05).The severity of headache of the experimen-tal group was lower than that of the control group.The total efficacy rate of the experimental group was higher than that of the control group(98.08% vs 86.54% ,χ2 =6.407 , P=0.040).Conclusion The combination of Flunarizine and Sumatriptan has better efficacy on acute cluster headache than Sumatriptan.