CAJ | 학술논문

　　目的探讨静吸复合麻醉对颅内手术患者麻醉用量及不良反应的影响。方法选取我院2012年1月至2012年12月采取静吸复合麻醉方式行颅内手术患者60例，随机分成A、B、C三组，分别给予患者不同麻醉用量，观察不同麻醉用量麻醉效果和不良反应情况。结果 A组不良反应3例，发生率为15.0%，B组9例（30.0%），C组21例（70.0%）；A组和B组麻醉效果差异明显（P＜0.05），B组和C组麻醉效果比较无显著差异（P＞0.05）。结论对于采取静吸复合麻醉方式行颅内手术患者，2～3μg/mL血浆靶浓度丙泊酚复合4～6ng/mL血浆靶浓度瑞芬太尼与3～5μg/ml丙泊酚复合6～8ng/mL血浆靶浓度瑞芬太尼麻醉效果与无明显差异，不良反应较少，值得进一步研究和临床推广应用。
　　목적탐토정흡복합마취대로내수술환자마취용량급불량반응적영향。방법선취아원2012년1월지2012년12월채취정흡복합마취방식행로내수술환자60례，수궤분성A、B、C삼조，분별급여환자불동마취용량，관찰불동마취용량마취효과화불량반응정황。결과 A조불량반응3례，발생솔위15.0%，B조9례（30.0%），C조21례（70.0%）；A조화B조마취효과차이명현（P＜0.05），B조화C조마취효과비교무현저차이（P＞0.05）。결론대우채취정흡복합마취방식행로내수술환자，2～3μg/mL혈장파농도병박분복합4～6ng/mL혈장파농도서분태니여3～5μg/ml병박분복합6～8ng/mL혈장파농도서분태니마취효과여무명현차이，불량반응교소，치득진일보연구화림상추엄응용。
?Objective?To study the static absorption dosage of compound anesthesia in patients with intracranial surgery anesthesia and the impact of adverse reactions. Methods From January 2012- December 2012 static absorption compound anesthesia ways line of 60 patients with intracranial surgery, were randomly divided into A, B, C three groups and were given different dosage of anesthetic patients, observe the different dosage of anesthetic effects and adverse reactions. Results Incidence of adverse reactions for group A, group B 9 cases (30.0%), 21 cases of group C (70.0%); Clear difference anesthetic effect in group A and group B (P<0.05), group B and group C anesthesia effect is no significant difference (P>0.05). Conclusion To adopt static absorption line compound anesthesia of intracranial surgery patients, 2~3 μg/mL plasma concentration of propofol target compound 4, 6 ng/mL target plasma concentration, fentanyl and 3~5 μg/mL propofol compound 6-8 ng/mL, fentanyl anesthesia target plasma concentration effect and no obvious difference, with less adverse reactions, worthy of further research and clinical application.