中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
16期
477-478,479
,共3页
杨珊%李建利%施明毅%谢燕%奚建
楊珊%李建利%施明毅%謝燕%奚建
양산%리건리%시명의%사연%해건
利肾胶囊%薄层色谱法%高效液相色谱法%质量标准
利腎膠囊%薄層色譜法%高效液相色譜法%質量標準
리신효낭%박층색보법%고효액상색보법%질량표준
Lishen Capsule%TLC%HPLC%quality standard
目的建立利肾胶囊的质量控制方法。方法采用薄层色谱法对方中木贼，鱼腥草进行定性鉴别，采用高效液相色谱法测定利肾胶囊中主要成分山奈素的含量。结果薄层色谱特征斑点清晰，专属性强，阴性对照无干扰；高效液相色谱法测定山奈素含量0.04～0.40μg在范围内线性关系良好（r=0.9999），平均回收率为98.73%，RSD=1.69%。结论该方法简便可靠、专属性强、重复性好，可用于该制剂的质量控制。
目的建立利腎膠囊的質量控製方法。方法採用薄層色譜法對方中木賊，魚腥草進行定性鑒彆，採用高效液相色譜法測定利腎膠囊中主要成分山奈素的含量。結果薄層色譜特徵斑點清晰，專屬性彊，陰性對照無榦擾；高效液相色譜法測定山奈素含量0.04～0.40μg在範圍內線性關繫良好（r=0.9999），平均迴收率為98.73%，RSD=1.69%。結論該方法簡便可靠、專屬性彊、重複性好，可用于該製劑的質量控製。
목적건립리신효낭적질량공제방법。방법채용박층색보법대방중목적，어성초진행정성감별，채용고효액상색보법측정리신효낭중주요성분산내소적함량。결과박층색보특정반점청석，전속성강，음성대조무간우；고효액상색보법측정산내소함량0.04～0.40μg재범위내선성관계량호（r=0.9999），평균회수솔위98.73%，RSD=1.69%。결론해방법간편가고、전속성강、중복성호，가용우해제제적질량공제。
Objective?To establish the method to control the quality of Lishen Capsule. Methods Equisetum and houttuynia in the preparation were identified by TLC.The content of kaempferol which is the effective substance in the preparation was determined by HPLC. Results Above herbs could be detected by TLC. The linear correlation of the kaempferol was good in the range of 0.04~0.40μg (r=0.9999) and the recovery was 98.73%(RSD=1.69%).Conclusion The method is feasible with good specificity and reproducibility, and can be applied to quality control of the production.
