CAJ | 학술논문

　　目的探讨肺泡表面活性物质（PS）治疗新生儿呼吸窘迫综合征（NRDS）的临床疗效。方法采用回顾资料法，2009年1月至2012年12月就诊我院新生儿重症监护室采用固尔苏治疗NRDS的患儿30例为观察组，同期未用固尔苏的NRDS患儿30例为对照组，分析比较两组患者的临床资料。结果观察组血气改善情况明显优于对照组，两组数据比较有统计学意义（P＜0.05）；呼吸机和氧的使用均明显少于对照组，两组数据比较有统计学意义（P＜0.05）。结论肺泡表面活性物质治疗新生儿呼吸窘迫综合征临床效果显著，可以有效缩短病程，降低病死率，具有积极的临床意义。
　　목적탐토폐포표면활성물질（PS）치료신생인호흡군박종합정（NRDS）적림상료효。방법채용회고자료법，2009년1월지2012년12월취진아원신생인중증감호실채용고이소치료NRDS적환인30례위관찰조，동기미용고이소적NRDS환인30례위대조조，분석비교량조환자적림상자료。결과관찰조혈기개선정황명현우우대조조，량조수거비교유통계학의의（P＜0.05）；호흡궤화양적사용균명현소우대조조，량조수거비교유통계학의의（P＜0.05）。결론폐포표면활성물질치료신생인호흡군박종합정림상효과현저，가이유효축단병정，강저병사솔，구유적겁적림상의의。
Objective Study of pulmonary surfactant (PS) in treatment of neonatal respiratory distress syndrome (NRDS) clinical curative effect. Method Retrospective data, in 2009 January -2012 year in December in our hospital neonatal intensive care unit by Curosurf for treatment of children with NRDS 30 cases for the observation group, the same period in the absence of Gulsu's 30 children with NRDS were selected as control group, analysis of the clinical data of the two groups were compared. Study of pulmonary surfactant (PS) in treatment of neonatal respiratory distress syndrome (NRDS) clinical curative effect. Result The observation group were significantly higher than those in control group, two groups of data were statistically significant (P<0.05); the ventilator and oxygen were significantly less than that in the control group, two groups of data were statistically significant (P<0.05). Conclusion Pulmonary surfactant on neonatal respiratory distress syndrome clinical effect is remarkable, can effectively shorten the course, reduce the mortality rate, has positive clinical significance