中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
16期
11-12
,共2页
子宫肌瘤%子宫肌瘤剥除术%子宫全切%附件切除%性激素
子宮肌瘤%子宮肌瘤剝除術%子宮全切%附件切除%性激素
자궁기류%자궁기류박제술%자궁전절%부건절제%성격소
Uterine fibroids%Uterine fibroids cystectomy%Hysterectomy%Oophorectomy%Sex hormone
目的研究子宫肌瘤不同的手术方式对患者内分泌功能的影响作用。方法107例子宫肌瘤患者根据不同术式分为观察组1（行子宫肌瘤剥除术）22例、观察组2（行子宫全切或次全切，保留双附件）67例，观察组3（行子宫全切，双附件切除）18例，比较各组研究对象手术前后性激素水平变化。结果观察组1术前、术后8周及术后24周性激素FSH、LH、E2均无统计学差异（P＞0.05）；观察组2术后8周 FSH、LH、E2与术前无统计学差异（P＞0.05）；术后24周 FSH、LH、E2与术前有统计学差异（P＜0.05）。FSH、LH出现升高， E2出现下降；观察组3术后8周 FSH、LH、E2与术前有统计学差异（P＜0.05）；术后24周 FSH、LH、E2与术前统计学差异有显著性（P＜0.01）。FSH、LH出现升高，E2出现下降；三组术后一年内出现围绝经症状比例分别为9.1%、23.9%、83.3%，存在统计学差异（P＜0.05），以观察组3最高。结论不同术式对子宫肌瘤患者内分泌功能影响不同，临床应根据患者选择合适手术方式。
目的研究子宮肌瘤不同的手術方式對患者內分泌功能的影響作用。方法107例子宮肌瘤患者根據不同術式分為觀察組1（行子宮肌瘤剝除術）22例、觀察組2（行子宮全切或次全切，保留雙附件）67例，觀察組3（行子宮全切，雙附件切除）18例，比較各組研究對象手術前後性激素水平變化。結果觀察組1術前、術後8週及術後24週性激素FSH、LH、E2均無統計學差異（P＞0.05）；觀察組2術後8週 FSH、LH、E2與術前無統計學差異（P＞0.05）；術後24週 FSH、LH、E2與術前有統計學差異（P＜0.05）。FSH、LH齣現升高， E2齣現下降；觀察組3術後8週 FSH、LH、E2與術前有統計學差異（P＜0.05）；術後24週 FSH、LH、E2與術前統計學差異有顯著性（P＜0.01）。FSH、LH齣現升高，E2齣現下降；三組術後一年內齣現圍絕經癥狀比例分彆為9.1%、23.9%、83.3%，存在統計學差異（P＜0.05），以觀察組3最高。結論不同術式對子宮肌瘤患者內分泌功能影響不同，臨床應根據患者選擇閤適手術方式。
목적연구자궁기류불동적수술방식대환자내분비공능적영향작용。방법107례자궁기류환자근거불동술식분위관찰조1（행자궁기류박제술）22례、관찰조2（행자궁전절혹차전절，보류쌍부건）67례，관찰조3（행자궁전절，쌍부건절제）18례，비교각조연구대상수술전후성격소수평변화。결과관찰조1술전、술후8주급술후24주성격소FSH、LH、E2균무통계학차이（P＞0.05）；관찰조2술후8주 FSH、LH、E2여술전무통계학차이（P＞0.05）；술후24주 FSH、LH、E2여술전유통계학차이（P＜0.05）。FSH、LH출현승고， E2출현하강；관찰조3술후8주 FSH、LH、E2여술전유통계학차이（P＜0.05）；술후24주 FSH、LH、E2여술전통계학차이유현저성（P＜0.01）。FSH、LH출현승고，E2출현하강；삼조술후일년내출현위절경증상비례분별위9.1%、23.9%、83.3%，존재통계학차이（P＜0.05），이관찰조3최고。결론불동술식대자궁기류환자내분비공능영향불동，림상응근거환자선택합괄수술방식。
Objective To study different surgical methods influence of endocrine function in patients with uterine fibroids. Methods 107 cases of uterine fibroids patients according to different operation was divided into the observation group 1 ( uterine fibroids cystectomy ) in 22 cases, the observation group 2 ( row hysterectomy or subtotal, retain double accessories ) in 67 cases, the observation group 3 ( line of hysterectomy, bilateral salpingo-oophorectomy ) in 18 cases, variability hormone levels before and after operation were compared among the three groups. Result Sex hormones FSH, LH, E2 observed in group 1 preoperative and postoperative 8 weeks and 24 weeks after the operation there was no significant difference (P>0.05); In the observation group 2, FSH, LH, E2 8 weeks after surgery and preoperative no statistical difference (P>0.05); FSH, LH, E2 24 weeks after surgery and preoperative had significant difference (P<0.05). FSH, LH increased, E2 decreased; In the observation group 3, FSH, LH, E2 8 weeks after surgery and preoperative had significant difference (P<0.05); FSH, LH, E2 after 24 weeks compared with those before operation, had significant statistical differences (P<0.01). FSH, LH increased, E2 decreased; the three group after a year of perimenopausal symptoms was respectively 9.1%, 23.9%, 83.3%, there was significant difference (P<0.05), to observe the 3 highest.conclusion Different surgical endocrine function in patients with uterine fibroids affect different clinical surgery should be based on the patient to choose the right way.
