CAJ | 학술논문

　　目的乳腺导管原位癌保乳术后辅助放疗的Meta分析。方法对相关的乳腺导管原位癌的临床试验的文献资料进行搜索，其中分别在万方数据库，中国期刊全文数据库，中国生物医学文献数据库，Pubmed等进行手工相关的检索。并且对相关的文献进行Meta的分析。结果在初步相关乳腺导管原位癌的初步文献搜索中可以找到有文献710篇，然后对不符合入选标准的相关乳腺导管原位癌文献进行排除，然后再对仔细查看文献，最终得到4篇文献能够纳入统计研究分析，共8个随机对照试验，共1221例患者进行统计分析。对于纳入研究分析的4篇报道对于乳腺导管原位癌患者采用保乳术后进行放疗以及其局部复发的关系进行Meta分析。非放疗组的局部复发率明显要高于放疗组，两组之间的差异具有统计学的意义。结论乳腺导管原位癌保乳术后辅助放疗能够有效降低患者术后的局部复发率，提高患者手术后的预后质量以及生活质量，延长患者的寿命。
　　목적유선도관원위암보유술후보조방료적Meta분석。방법대상관적유선도관원위암적림상시험적문헌자료진행수색，기중분별재만방수거고，중국기간전문수거고，중국생물의학문헌수거고，Pubmed등진행수공상관적검색。병차대상관적문헌진행Meta적분석。결과재초보상관유선도관원위암적초보문헌수색중가이조도유문헌710편，연후대불부합입선표준적상관유선도관원위암문헌진행배제，연후재대자세사간문헌，최종득도4편문헌능구납입통계연구분석，공8개수궤대조시험，공1221례환자진행통계분석。대우납입연구분석적4편보도대우유선도관원위암환자채용보유술후진행방료이급기국부복발적관계진행Meta분석。비방료조적국부복발솔명현요고우방료조，량조지간적차이구유통계학적의의。결론유선도관원위암보유술후보조방료능구유효강저환자술후적국부복발솔，제고환자수술후적예후질량이급생활질량，연장환자적수명。
Objective Breast ductal carcinoma in situ the milk postoperative adjuvant radiation therapy of Meta analysis. Methods The related breast ductal carcinoma in situ clinical trials of the literature search, which respectively in ten thousand party database, China journal full text database and Chinese biomedical literature database of manual related retrieval. And the related literature Meta analysis. Results In preliminary related breast ductal carcinoma in situ initial literature search can be found in the 710 references are, then do not conform to the inclusion criteria related breast ductal carcinoma in situ literature was ruled out, and then again to carefully check the literature, and ultimately the four articles can into the statistical analysis, a total of eight randomized controlled trial, 1221 patients were statistically analyzed. For research and analysis into four reports for patients with ductal carcinoma in situ by the milk in the radiation and the relationship between local recurrence of Meta analysis. The radiation group of local recurrence rate significantly higher than the radiation group, the difference between the two groups have statistical significance. Conclusion Breast ductal carcinoma in situ the milk postoperative adjuvant radiation therapy can effectively reduce patients postoperative local recurrence rate and improve the prognosis of patients after operation quality and the quality of life and prolong the life of the patients.