CAJ | 학술논문

　　目的观察紫龙金片联合化疗治疗中晚期原发性肝癌与单纯化疗的临床效果。方法治疗组（紫龙金+化疗）16例，对照组（单纯化疗）16例。评定其疗效和免疫功能变化、生活质量和毒副作用。结果治疗组疗效好于对照组，病灶缓解率（CR+PR）为18.75%，免疫功能和生活质量明显改善，治疗后与对照组比较有显著差异（P<0.01)。治疗组的毒副作用明显低于对照组，经统计学处理有显著性差异（P<0.05）。结论紫龙金片对中晚期原发性肝癌患者有一定的疗效，免疫功能与生活质量明显改善。可能的机理是调节细胞免疫功能。
　　목적관찰자룡금편연합화료치료중만기원발성간암여단순화료적림상효과。방법치료조（자룡금+화료）16례，대조조（단순화료）16례。평정기료효화면역공능변화、생활질량화독부작용。결과치료조료효호우대조조，병조완해솔（CR+PR）위18.75%，면역공능화생활질량명현개선，치료후여대조조비교유현저차이（P<0.01)。치료조적독부작용명현저우대조조，경통계학처리유현저성차이（P<0.05）。결론자룡금편대중만기원발성간암환자유일정적료효，면역공능여생활질량명현개선。가능적궤리시조절세포면역공능。
Objective:It is to observe curative effect of Zilongjin Tablet combined with chemotherapy and its synergism and detoxication on moderate and advanced of primary hepatic celular carcinomas Methods:The patients were divided randomly into two groups.The treated group(n=16)was treated chemotherapy plus Zilongjin Tablets;and the control group(n=16)treated with chemotherapy alone.Treatment effectiveness was measured with Complete remission and Partial remission(CR+PR)..Result:In the treatment group(16),clinical effect, ,improvement of life quality and immunologic function were better than those in control group(16)The toxic side-effects caused by chemotherapy in the treatment group were lower than that in the control group(p<0.05) .Conclusion: Zilongjin Tablet can enhance the therapeutic effect, improve life quality and reduce the side-effects of chemotherapy.One possible mechanism is the modulation of celular immune function.