CAJ | 학술논문

目的：对比地佐辛与芬太尼在子宫肌瘤切除术中的镇痛效果及安全性。方法将我院行子宫肌瘤切除术的68例患者随机分为观察组和对照组,对照组采用芬太尼镇痛,观察组给予地佐辛。对比两组患者术后VAS和Ramsay评分,并记录不良反应发生情况。结果观察组术后1、3、6 h VAS评分显著低于对照组,两组比较差异有统计学意义(P<0．05)；观察组术后1、3、6、24 h Ramsay评分明显优于对照组,两组比较差异有统计学意义(P<0．05)。观察组恶心、呕吐发生率显著低于对照组(χ2=5．162,P<0．05),其余各不良反应发生率与对照组比较差异无统计学意义(P>0．05)。结论地佐辛对子宫肌瘤切除术的镇痛效果优于芬太尼,且胃肠道不良反应率较低,安全有效,值得临床推广应用。
목적：대비지좌신여분태니재자궁기류절제술중적진통효과급안전성。방법장아원행자궁기류절제술적68례환자수궤분위관찰조화대조조,대조조채용분태니진통,관찰조급여지좌신。대비량조환자술후VAS화Ramsay평분,병기록불량반응발생정황。결과관찰조술후1、3、6 h VAS평분현저저우대조조,량조비교차이유통계학의의(P<0．05)；관찰조술후1、3、6、24 h Ramsay평분명현우우대조조,량조비교차이유통계학의의(P<0．05)。관찰조악심、구토발생솔현저저우대조조(χ2=5．162,P<0．05),기여각불량반응발생솔여대조조비교차이무통계학의의(P>0．05)。결론지좌신대자궁기류절제술적진통효과우우분태니,차위장도불량반응솔교저,안전유효,치득림상추엄응용。
Objective To compare the analgesic effect and safety of dezocine and fentanyl on hysteromyomec-tomy. Methods 68 patients underwent myomectomy in our hospital were randomly divided into observation group and control group, control group was given fentanyl analgesia, observation group was given dezocine. The postoperative VAS and Ramsay score of the two groups were compared and the occurrence of adverse reactions was recorded. Results The VAS score of observation group was significantly lower than that of control group after 1,3,6 h of operation, there was significant difference between the two groups (P<0. 05);the Ramsay score of observation group was signifi-cantly better than that of control group after 1,3,6,24 h of operation,there was significant difference between the two groups (P<0. 05). The incidence of nausea,vomiting of observation group was significantly lower than those of con-trol group (χ2 =5. 162,P<0. 05),the incidence of adverse reactions of observation group had no significant difference compared with control group ( P >0. 05 ) . Conclusion The effect of dezocine on uterine myomectomy analgesic is better than fentanyl,and gastrointestinal adverse reaction rate is low,it is safe and effective,worthy of clinical applica-tion.